It is shown that structural changes of the phototoxic anti-cancer drug flutamide after its compartmentalization in unilamellar phospholipid bilayer vesicles lead to a highly selective modification of the photochemical outcome, locking the main photodegradation pathways observed in homogeneous media and unlocking a new and more efficient photoreactive channel. RI Sortino, Salvatore/E-4684-2011
New insight on the photoreactivity of the phototoxic anti-cancer flutamide: photochemical pathways selectively locked and unlocked by structural changes upon drug compartmentalization in phospholipid bilayer vesicles
SORTINO, Salvatore;
2001-01-01
Abstract
It is shown that structural changes of the phototoxic anti-cancer drug flutamide after its compartmentalization in unilamellar phospholipid bilayer vesicles lead to a highly selective modification of the photochemical outcome, locking the main photodegradation pathways observed in homogeneous media and unlocking a new and more efficient photoreactive channel. RI Sortino, Salvatore/E-4684-2011File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.