It is shown that structural changes of the phototoxic anti-cancer drug flutamide after its compartmentalization in unilamellar phospholipid bilayer vesicles lead to a highly selective modification of the photochemical outcome, locking the main photodegradation pathways observed in homogeneous media and unlocking a new and more efficient photoreactive channel. RI Sortino, Salvatore/E-4684-2011

New insight on the photoreactivity of the phototoxic anti-cancer flutamide: photochemical pathways selectively locked and unlocked by structural changes upon drug compartmentalization in phospholipid bilayer vesicles

SORTINO, Salvatore;
2001-01-01

Abstract

It is shown that structural changes of the phototoxic anti-cancer drug flutamide after its compartmentalization in unilamellar phospholipid bilayer vesicles lead to a highly selective modification of the photochemical outcome, locking the main photodegradation pathways observed in homogeneous media and unlocking a new and more efficient photoreactive channel. RI Sortino, Salvatore/E-4684-2011
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11769/36061
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