In order to enhance hydrophilicity and complexing properties of amino-phosphonates we synthesized a large variety of these compounds possessing one or two carboxylic groups in the aromatic ring(s). Such groups could facilitate enantiomer resolution and can be used for preparing a variety of interesting compounds as well as polycondensates. Characterization was performed by H-1-NMR and MS-FAB techniques. AU compounds synthesized are crystalline high melting materials soluble in water and/or in strong polar solvents, rendering them attractive both for complexation studies and biological applications.
Methyl-amino-phosphonic acid di-alkyl esters containing free carboxylic groups. Synthesis and characterization
FAILLA, Salvatore;
1995-01-01
Abstract
In order to enhance hydrophilicity and complexing properties of amino-phosphonates we synthesized a large variety of these compounds possessing one or two carboxylic groups in the aromatic ring(s). Such groups could facilitate enantiomer resolution and can be used for preparing a variety of interesting compounds as well as polycondensates. Characterization was performed by H-1-NMR and MS-FAB techniques. AU compounds synthesized are crystalline high melting materials soluble in water and/or in strong polar solvents, rendering them attractive both for complexation studies and biological applications.File in questo prodotto:
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