Objectives: To investigate the relationships between occupational exposure, smoking, and heavy metals (Pb, Hg, Ni, Cd, As, V) concentrations in men living in an area at environmental risk. Methods: Ninety six men with mean (±SEM) age of 33.2±0.6 years, living in Melilli (Priolo-Augusta-Melilli industrial triangle in Eastern Sicily, Italy), were recruited. Of these, 53.1% were industrial workers, 37.5% were smokers, and 15.6% were industrial workers and smokers. Blood and seminal plasma Pb, Hg, Cd, Ni, As, V concentrations were measured by a Perkin-Elmer-Elan DRC-e ICP-MS. Sperm parameters were evaluated according to the WHO 1999 guidelines. Results: Industrial workers had higher median concentrations of Pb (10.96 vs. 9.40), Hg (5.80 vs. 4.64), and Ni (13.34 vs. 10.02) in blood (μg/L); and Pb (25.37 vs. 20.22), Cd (1.57 vs. 1.15), and As (2.90 vs. 2.43) in the seminal plasma (μg/L) compared with non-industrial workers. Smokers had higher median concentrations of Pb, Cd, and Hg in blood and V in the seminal plasma vs. non smokers, both in industrial and non-industrial workers. Eighty out of 96 (83.3%) men had asthenozoospermia. Conclusions: Occupational and environmental exposure to heavy metals results in higher levels of these toxicants in blood and seminal plasma and this is associated with sperm motility impairment.
|Titolo:||Relationship between occupational exposure and heavy metal levels in men living in an Eastern Sicily industrial area|
|Data di pubblicazione:||2012|
|Appare nelle tipologie:||1.5 Abstract in rivista|