The Authors have carried out an experimental study to evaluate the interference of sub.inhibitory concentrations of clindamycin on the adherence of slim e producing S.epidermidis to surgical nets and its ability to infect rabbits. (0 rabbits divided into 4 groups (A,B,C, and D), underwent sham operation of the abdominal zone and were sewn up with steril nets, infected netis and sub-MIC of clindamycin equal to 1/8 MIC, respectively. The results obtained stressed a different survival rate 12 days after operation: 95% in group A, 35% in group B; 100% in gruop C and 95% in group D. This data were confirmed by the results obtained using MES ( Cambridge Stereoscan 150 KM2). from our research an excellent clindamycin inhibitory activity on the pathogenicity of slime producing staphilococci emerged.
INTERFERENZA DELLA CLINDAMICINA SULL’INFEZIONE CUTANEA DEL CONIGLIO DOVUTA A FILI DI SUTUTA INFETTATI CON S.EPIDERMIDIS PRODUTTORE DI SLIME.
CHISARI, Giuseppe
1990-01-01
Abstract
The Authors have carried out an experimental study to evaluate the interference of sub.inhibitory concentrations of clindamycin on the adherence of slim e producing S.epidermidis to surgical nets and its ability to infect rabbits. (0 rabbits divided into 4 groups (A,B,C, and D), underwent sham operation of the abdominal zone and were sewn up with steril nets, infected netis and sub-MIC of clindamycin equal to 1/8 MIC, respectively. The results obtained stressed a different survival rate 12 days after operation: 95% in group A, 35% in group B; 100% in gruop C and 95% in group D. This data were confirmed by the results obtained using MES ( Cambridge Stereoscan 150 KM2). from our research an excellent clindamycin inhibitory activity on the pathogenicity of slime producing staphilococci emerged.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
