Two monomers for the syntheses of conformationally restricted peptide nucleic acids were synthesized through a simple procedure, involving an asymmetric 1,3-dipolar cycloaddition chemistry as a key step, from common starting materials in 3 and 5 steps, and 58.8% and 30.5% overall yields, respectively.
High-yield synthesis of pyrrolidinyl PNA monomers
CHIACCHIO, Ugo;CORSARO, Antonino;PISTARA', Venerando;
2011-01-01
Abstract
Two monomers for the syntheses of conformationally restricted peptide nucleic acids were synthesized through a simple procedure, involving an asymmetric 1,3-dipolar cycloaddition chemistry as a key step, from common starting materials in 3 and 5 steps, and 58.8% and 30.5% overall yields, respectively.File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
55) Tet Lett 2011, 52, 6003-6006.pdf
solo gestori archivio
Licenza:
Non specificato
Dimensione
571.94 kB
Formato
Adobe PDF
|
571.94 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
