The results of studies on the design of a heterocyclic scaffold for the dynorphin A pharmacophore and on structure-affinity relationships in the MPCB/CCB series are described. The representative ligands provide insights to binding modes of benzomorphan derivatives to the κ opioid receptor.

Specific kappa opioid receptor agonists

RONSISVALLE, Giuseppe;MARRAZZO, Agostino;PASQUINUCCI, Lorella Giuseppina;
2001-01-01

Abstract

The results of studies on the design of a heterocyclic scaffold for the dynorphin A pharmacophore and on structure-affinity relationships in the MPCB/CCB series are described. The representative ligands provide insights to binding modes of benzomorphan derivatives to the κ opioid receptor.
2001
(−)-cis-N-Normetazocine; Peptidomimetics; Kappa opioid receptor; Kappa opioid agonists
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11769/931
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