PASQUINUCCI, Lorella Giuseppina
PASQUINUCCI, Lorella Giuseppina
SCIENZE DEL FARMACO E DELLA SALUTE (DSFS) (Department of Drug and Health Sciences)
((2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist
2019-01-01 Pasquinucci, Lorella; Turnaturi, Rita; Calò, Girolamo; Pappalardo, Francesco; Ferrari, Federica; Russo, Giulia; Arena, Emanuela; Montenegro, Lucia; Chiechio, Santina; Prezzavento, Orazio; Parenti, Carmela
(+)-and (−)-Phenazocine enantiomers: evaluation of their dual opioid agonist/σ1 antagonist properties and antinociceptive effects
2017-01-01 Prezzavento, Orazio; Arena, Emanuela; Sánchez-Fernández, Cristine; Turnaturi, Rita; Parenti, Carmela; Marrazzo, Agostino; Catalano, Roberto; Amata, Emanuele; Pasquinucci, Lorella; Cobos J., Enrique
(+)-cis-N-ethyleneamino-N-normetazocine derivatives. Novel and selective sigma ligands with antagonist properties
1998-01-01 Ronsisvalle, G; Marrazzo, Agostino; Prezzavento, Orazio; Pasquinucci, Lorella Giuseppina; Vittorio, F; Pittala', Valeria; Pappalardo, Ms; Cacciaguerra, S; Spampinato, S.
A New LP1 analogue is used to better understand MOR ligand Binding Domain and its mechanisms of activation
2016-01-01 Ronsisvalle, Simone; Aricò, G.; Panarello, F.; Spadaro, Angelo; Pasquinucci, Lorella Giuseppina; Pappalardo, M. S.; Parenti, Carmela; Ronsisvalle, N.
A new Sigma-1 Receptor antagonist in Chronic Pain Treatment: (+)-2R/S-LP2 effects in inflammatory and neuropathic pain
2022-01-01 Spoto, Salvatore; Pasquinucci, Lorella Giuseppina; Turnaturi, Rita; Costanzo, Giuliana; Chiechio, Santina; Vicario, Nunzio; Parenti, Rosalba; Marrazzo, Agostino; Amata, Emanuele; Parenti, Carmela
An LP1 analogue, selective MOR agonist with a peculiar pharmacological profile, used to scrutiny the ligand binding domain
2016-01-01 Ronsisvalle, Simone; Aricò, G; Panarello, F; Spadaro, Angelo; Pasquinucci, Lorella Giuseppina; Pappalardo, Ms; Parenti, Carmela; Ronsisvalle, N.
Analgesici oppioidi: nuove opportunità nella terapia del dolore
file da validare2007-01-01 Pasquinucci, Lorella Giuseppina
Analoghi non-peptidici della dinorfina A(1-8): progettazione, sintesi e valutazione farmacologica di agonisti ad elevata selettività Kappa.
file da validare1998-01-01 Pasquinucci, Lorella Giuseppina; Pittala', Valeria; Spampinato, S.; Ronsisvalle, G.
ANTIALLODINIC AND ANTIHYPERALGESIC EFFECTS OF LP1, AN OPIOID MULTITARGET LIGAND, IN INFLAMMATORY AND NEUROPATHIC PAIN STATES
file da validare2012-01-01 Aricò, G; Parenti, Carmela; Pasquinucci, Lorella Giuseppina; Turnaturi, Rita; Ronsisvalle, G; Scoto, G. M.
Antiallodinic and antihyperalgesic effects of LP1, an opioid multitarget ligand, in inflammatory and neurophatic pain states
file da validare2012-01-01 Aricò, G; Parenti, Carmela; Pasquinucci, Lorella Giuseppina; Turnaturi, R; Ronsisvalle, G; Scoto, Gm
Antinociceptive profile of LP1, a non-peptide multitarget opioid ligand.
2012-01-01 Parenti, Carmela; Turnaturi, Rita; Aricò, G; Marrazzo, Agostino; Prezzavento, Orazio; Ronsisvalle, Simone; Scoto, Giovanna Maria; Ronsisvalle, Giuseppe; Pasquinucci, Lorella Giuseppina
Antioxidant properties and pharmacokinetic studies of new selective σ1 bifunctional ligands
file da validare2015-01-01 Marrazzo, Agostino; Arena, Emanuela; Cacciatore, Ivana; Cerasa Laura, S.; Amata, Emanuele; Pittala', Valeria; Pasquinucci, Lorella Giuseppina; Turkez, Hasan; Di Stefano, Antonio; Prezzavento, Orazio
Antiproliferative activity of phenylbutyrate ester of haloperidol metabolite II [(±)-MRJF4] in prostate cancer cells
2011-01-01 Marrazzo, Agostino; Fiorito, J; Zappalà, L; Prezzavento, Orazio; Ronsisvalle, Simone; Pasquinucci, Lorella Giuseppina; Scoto, Giovanna Maria; Bernardini, Renato; Ronsisvalle, G.
Benzomorphan scaffold for opioid analgesics and pharmacological tools development: A comprehensive review
2018-01-01 Turnaturi, Rita; Marrazzo, Agostino; Parenti, Carmela; Pasquinucci, Lorella
Benzomorphan skeleton, a versatile scaffold for different targets: A comprehensive review
2018-01-01 Turnaturi, Rita; Montenegro, Lucia; Marrazzo, Agostino; Parenti, Rosalba; Pasquinucci, Lorella; Parenti, Carmela
Benzomorphan-based opioid ligands with mixed m agonist/d antagonist activity
file da validare2007-01-01 Pasquinucci, Lorella Giuseppina; Marrazzo, Agostino; Prezzavento, O; Ronsisvalle, G.
Bivalent opioid peptides synthesized from μ selective monomers display preferential selectivity for δ receptors
file da validare1990-01-01 Ronsisvalle, G; Pappalardo, Ms; Pasquinucci, Lorella Giuseppina; Vittorio, F; Salvadori, S; Spampinato, S; Cavicchini, E; Ferri, S.
Bivalent opioid-peptides synthesized from mu-selective monomers display preferential selectivity for delta-receptors
file da validare1990-01-01 Ronsisvalle, Giuseppe; Pappalardo, Ms; Pasquinucci, Lorella Giuseppina; Vittorio, F; Salvadori, S; Spampinato, S; Cavicchini, E; Ferri, S.
Caspase-3 activation in human melanoma A375 cell line by a novel selective sigma-2 agonist
2016-01-01 Ronsisvalle, Simone; Aricò, Giuseppina; Cova, ANNA MARIA; Blanco, Palma; Amata, Emanuele; Pappalardo, Maria Sebastiana; Pasquinucci, Lorella; Spadaro, Angelo; Ronsisvalle, Nicole
CCB - A novel analog of MPCB with high binding affinity and specific kappa opioid receptor agonist
file da validare1994-01-01 Ronsisvalle, Giuseppe; Prezzavento, Orazio; Pasquinucci, Lorella Giuseppina; Carboni, L; Pistacchio, E; Spampinato, S.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| ((2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist | 1-gen-2019 | Pasquinucci, Lorella; Turnaturi, Rita; Calò, Girolamo; Pappalardo, Francesco; Ferrari, Federica; Russo, Giulia; Arena, Emanuela; Montenegro, Lucia; Chiechio, Santina; Prezzavento, Orazio; Parenti, Carmela | |
| (+)-and (−)-Phenazocine enantiomers: evaluation of their dual opioid agonist/σ1 antagonist properties and antinociceptive effects | 1-gen-2017 | Prezzavento, Orazio; Arena, Emanuela; Sánchez-Fernández, Cristine; Turnaturi, Rita; Parenti, Carmela; Marrazzo, Agostino; Catalano, Roberto; Amata, Emanuele; Pasquinucci, Lorella; Cobos J., Enrique | |
| (+)-cis-N-ethyleneamino-N-normetazocine derivatives. Novel and selective sigma ligands with antagonist properties | 1-gen-1998 | Ronsisvalle, G; Marrazzo, Agostino; Prezzavento, Orazio; Pasquinucci, Lorella Giuseppina; Vittorio, F; Pittala', Valeria; Pappalardo, Ms; Cacciaguerra, S; Spampinato, S. | |
| A New LP1 analogue is used to better understand MOR ligand Binding Domain and its mechanisms of activation | 1-gen-2016 | Ronsisvalle, Simone; Aricò, G.; Panarello, F.; Spadaro, Angelo; Pasquinucci, Lorella Giuseppina; Pappalardo, M. S.; Parenti, Carmela; Ronsisvalle, N. | |
| A new Sigma-1 Receptor antagonist in Chronic Pain Treatment: (+)-2R/S-LP2 effects in inflammatory and neuropathic pain | 1-gen-2022 | Spoto, Salvatore; Pasquinucci, Lorella Giuseppina; Turnaturi, Rita; Costanzo, Giuliana; Chiechio, Santina; Vicario, Nunzio; Parenti, Rosalba; Marrazzo, Agostino; Amata, Emanuele; Parenti, Carmela | |
| An LP1 analogue, selective MOR agonist with a peculiar pharmacological profile, used to scrutiny the ligand binding domain | 1-gen-2016 | Ronsisvalle, Simone; Aricò, G; Panarello, F; Spadaro, Angelo; Pasquinucci, Lorella Giuseppina; Pappalardo, Ms; Parenti, Carmela; Ronsisvalle, N. | |
| Analgesici oppioidi: nuove opportunità nella terapia del dolore | 1-gen-2007 | Pasquinucci, Lorella Giuseppina | file da validare |
| Analoghi non-peptidici della dinorfina A(1-8): progettazione, sintesi e valutazione farmacologica di agonisti ad elevata selettività Kappa. | 1-gen-1998 | Pasquinucci, Lorella Giuseppina; Pittala', Valeria; Spampinato, S.; Ronsisvalle, G. | file da validare |
| ANTIALLODINIC AND ANTIHYPERALGESIC EFFECTS OF LP1, AN OPIOID MULTITARGET LIGAND, IN INFLAMMATORY AND NEUROPATHIC PAIN STATES | 1-gen-2012 | Aricò, G; Parenti, Carmela; Pasquinucci, Lorella Giuseppina; Turnaturi, Rita; Ronsisvalle, G; Scoto, G. M. | file da validare |
| Antiallodinic and antihyperalgesic effects of LP1, an opioid multitarget ligand, in inflammatory and neurophatic pain states | 1-gen-2012 | Aricò, G; Parenti, Carmela; Pasquinucci, Lorella Giuseppina; Turnaturi, R; Ronsisvalle, G; Scoto, Gm | file da validare |
| Antinociceptive profile of LP1, a non-peptide multitarget opioid ligand. | 1-gen-2012 | Parenti, Carmela; Turnaturi, Rita; Aricò, G; Marrazzo, Agostino; Prezzavento, Orazio; Ronsisvalle, Simone; Scoto, Giovanna Maria; Ronsisvalle, Giuseppe; Pasquinucci, Lorella Giuseppina | |
| Antioxidant properties and pharmacokinetic studies of new selective σ1 bifunctional ligands | 1-gen-2015 | Marrazzo, Agostino; Arena, Emanuela; Cacciatore, Ivana; Cerasa Laura, S.; Amata, Emanuele; Pittala', Valeria; Pasquinucci, Lorella Giuseppina; Turkez, Hasan; Di Stefano, Antonio; Prezzavento, Orazio | file da validare |
| Antiproliferative activity of phenylbutyrate ester of haloperidol metabolite II [(±)-MRJF4] in prostate cancer cells | 1-gen-2011 | Marrazzo, Agostino; Fiorito, J; Zappalà, L; Prezzavento, Orazio; Ronsisvalle, Simone; Pasquinucci, Lorella Giuseppina; Scoto, Giovanna Maria; Bernardini, Renato; Ronsisvalle, G. | |
| Benzomorphan scaffold for opioid analgesics and pharmacological tools development: A comprehensive review | 1-gen-2018 | Turnaturi, Rita; Marrazzo, Agostino; Parenti, Carmela; Pasquinucci, Lorella | |
| Benzomorphan skeleton, a versatile scaffold for different targets: A comprehensive review | 1-gen-2018 | Turnaturi, Rita; Montenegro, Lucia; Marrazzo, Agostino; Parenti, Rosalba; Pasquinucci, Lorella; Parenti, Carmela | |
| Benzomorphan-based opioid ligands with mixed m agonist/d antagonist activity | 1-gen-2007 | Pasquinucci, Lorella Giuseppina; Marrazzo, Agostino; Prezzavento, O; Ronsisvalle, G. | file da validare |
| Bivalent opioid peptides synthesized from μ selective monomers display preferential selectivity for δ receptors | 1-gen-1990 | Ronsisvalle, G; Pappalardo, Ms; Pasquinucci, Lorella Giuseppina; Vittorio, F; Salvadori, S; Spampinato, S; Cavicchini, E; Ferri, S. | file da validare |
| Bivalent opioid-peptides synthesized from mu-selective monomers display preferential selectivity for delta-receptors | 1-gen-1990 | Ronsisvalle, Giuseppe; Pappalardo, Ms; Pasquinucci, Lorella Giuseppina; Vittorio, F; Salvadori, S; Spampinato, S; Cavicchini, E; Ferri, S. | file da validare |
| Caspase-3 activation in human melanoma A375 cell line by a novel selective sigma-2 agonist | 1-gen-2016 | Ronsisvalle, Simone; Aricò, Giuseppina; Cova, ANNA MARIA; Blanco, Palma; Amata, Emanuele; Pappalardo, Maria Sebastiana; Pasquinucci, Lorella; Spadaro, Angelo; Ronsisvalle, Nicole | |
| CCB - A novel analog of MPCB with high binding affinity and specific kappa opioid receptor agonist | 1-gen-1994 | Ronsisvalle, Giuseppe; Prezzavento, Orazio; Pasquinucci, Lorella Giuseppina; Carboni, L; Pistacchio, E; Spampinato, S. | file da validare |