Introduction: Alpha-fetoprotein (AFP) is an oncofetal protein produced by hepatocellular carcinoma (HCC). AFP level canalso be elevated in other neoplastic or non-neoplastic conditions. An elevated AFP level has high diagnostic significance forHCC; at a level of >200 ng/mL, the probability of HCC is >90%. The aim of the present paper is to report a patient whounderwent curative resection of HCC, who had a persistently elevated AFP level postoperatively but did not developrecurrence during a 2-year follow-up period. A review of the literature is also presented.Case report: An 82-year-old male was referred following a computed tomography scan showing a 160 mm diameter massin the left lobe of the liver. This huge mass was diagnosed as HCC, arising in the absence of cirrhosis or viral hepatitis. Aftertumor removal, the patient’s high AFP level persisted for 2 years.Conclusion: As steatosis was the only pathological change in the remnant liver, this may have caused the persistentlyelevated AFP level in this patient.
|Titolo:||Persistent increase in alpha-fetoprotein level in a patient without underlying liver disease who underwent curative resection of hepatocellular carcinoma. A case report and review of the literature|
ARDIRI, ANNALISA MARIA [Membro del Collaboration Group]
BERTINO, Gaetano [Membro del Collaboration Group]
|Data di pubblicazione:||2012|
|Appare nelle tipologie:||1.1 Articolo in rivista|