Background and aim:The relationship between celiac disease and inflammatory bowel disease (IBD) is still controversial and may be related to the different geographic areas. The aim of this study was to compare the prevalence of IBD in a cohort of celiac patients of an eastern Sicily area (Italy) to the prevalence of IBD in the only existing study in italian population. Material and methods:A database of patients (474 M–794 F, aged 18 to 77 yrs) with celiac disease seen in our hospital between 2000 and 2010 was analyzed. All celiac disease patients were diagnosed according to current criteria by serology and jejunal biopsy. IBD was identified by clinical history supported by endoscopic and pathologic confirmation. The prevalence of IBD in celiac patients was compared to the prevalence of IBD in the population of the metropolitan area of Florence. The data were analyzed using chi-square test with Yates correction for continuity. Results:Considering all the 1268 celiac patients, the prevalence of IBD was 6.35‰ in celiac patients vs 1.61‰ in non celiac population (p<0.01). However the difference between the prevalence of both UC (6.43‰ celiac patients vs 1.55‰ non celiac population, p<0.001) and CD (4.30‰ celiac patients vs 0.43‰ non celiac population, p<0.001) was significant only in males while no significant difference in prevalence of IBD was found in celiac females as compared to non celiac population. Conclusions:Within our cohort of patients with celiac disease, IBD was significantly higher than in general population. The difference was significant only in males and not in females. Of course the limitation of this study was to compare two populations of different italian geographical areas. However as far as we know there is no epidemiological study of sicilian population.
|Titolo:||PREVALENCE OF INFLAMMATORY BOWEL DISEASE IN PATIENTS WITH CELIAC DISEASE IN EASTERN SICILY AREA|
|Data di pubblicazione:||2011|
|Appare nelle tipologie:||4.2 Abstract in Atti di convegno|
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