Wastewater-Based Epidemiology (WBE) is a crucial tool for monitoring public health, detecting pathogens, drugs, and antimicrobial resistance in the population. This approach enables dynamic and community-based observation, essential for addressing global challenges such as pandemics and antibiotic resistance. The project monitored SARS-CoV-2 in 316 urban wastewater samples collected between November 2021 and October 2024 from three wastewater treatment plants in Eastern Sicily and evaluated antimicrobial resistance (AMR) in a selection of samples. The data revealed seasonal fluctuations of the virus, correlations between its concentration and the presence of resistance genes (ARGs) in specific samples, and effective post-treatment reduction. These results confirm the role of wastewater as key indicators and highlight the need for an integrated "One Health" approach to protect human and environmental health.
L'epidemiologia basata sulle acque reflue (Wastewater-Based Epidemiology, WBE) è uno strumento cruciale per monitorare la salute pubblica, rilevando patogeni, farmaci e resistenze antimicrobiche nella popolazione. Questo approccio consente un'osservazione dinamica e comunitaria, essenziale per affrontare sfide globali come pandemie e antibiotico-resistenza. Il progetto ha monitorato SARS-CoV-2 in 316 campioni di reflui urbani raccolti tra novembre 2021 e ottobre 2024 in tre impianti di depurazione della Sicilia orientale e valutato la resistenza antimicrobica (AMR) in una selezione di campioni. I dati hanno evidenziato fluttuazioni stagionali del virus, correlazioni tra la sua concentrazione e la presenza di geni di resistenza (ARG) in campioni specifici, e un'efficace riduzione post-trattamento. Questi risultati confermano il ruolo delle acque reflue come indicatori chiave e sottolineano la necessità di un approccio integrato "One Health" per la tutela della salute umana e ambientale.
Green strategies for Public Health: the application of waste-water epidemiology to monitor and prevent antimicrobial resistance and pandemics / La Rosa, Maria Clara. - (2024 Dec 18).
Green strategies for Public Health: the application of waste-water epidemiology to monitor and prevent antimicrobial resistance and pandemics.
LA ROSA, MARIA CLARA
2024-12-18
Abstract
Wastewater-Based Epidemiology (WBE) is a crucial tool for monitoring public health, detecting pathogens, drugs, and antimicrobial resistance in the population. This approach enables dynamic and community-based observation, essential for addressing global challenges such as pandemics and antibiotic resistance. The project monitored SARS-CoV-2 in 316 urban wastewater samples collected between November 2021 and October 2024 from three wastewater treatment plants in Eastern Sicily and evaluated antimicrobial resistance (AMR) in a selection of samples. The data revealed seasonal fluctuations of the virus, correlations between its concentration and the presence of resistance genes (ARGs) in specific samples, and effective post-treatment reduction. These results confirm the role of wastewater as key indicators and highlight the need for an integrated "One Health" approach to protect human and environmental health.File | Dimensione | Formato | |
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PhD Thesis- Maria Clara La Rosa.pdf
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