This paper is concerned with analytical investigations on the competition between cancer cells and immune system cells. Specifically the role of the B-cells and T-cells in the evolution of cancer cells is taken into account. The mathematical model is a Kolmogorov-type system of three evolution equations where the growth rate of the cells is described by logistic law and the response of B-cells and T-cells is modeled according to Holling type-II function. The stability analysis of equilibrium points is performed and the persistence of the model is proved.
Persistence analysis in a Kolmogorov-type model for cancer-immune system competition
PAPPALARDO, FRANCESCO;PENNISI, MARZIO ALFIO;RAGUSA, Maria Alessandra
2013-01-01
Abstract
This paper is concerned with analytical investigations on the competition between cancer cells and immune system cells. Specifically the role of the B-cells and T-cells in the evolution of cancer cells is taken into account. The mathematical model is a Kolmogorov-type system of three evolution equations where the growth rate of the cells is described by logistic law and the response of B-cells and T-cells is modeled according to Holling type-II function. The stability analysis of equilibrium points is performed and the persistence of the model is proved.File in questo prodotto:
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