Relapsing-Remitting Multiple Scleroris and the role of Vitamin D: an agent based model

Multiple sclerosis is an appalling disease which destroys the insulatic covers of the connections between neurons, causing disability and death. Its etiology is not yet fully understood and causes remain still unknown; therefore mathematical and computational models can help to test and verify biological hypoteses, and to understand the immune mechanisms involved. We present an extension of an agent based model that demonstrated able to describe the most common form of multiple sclerosis (relapsing-remitting) coupled with the presence of an important external factor that can improve the disease course: Vitamin D. We investigate the role of Vitamin D by a qualitative point of view, taking into account its well known immunomodulatory mechanisms