We present a further step in developing an in silico model that simulates the immune system responses to tumor cells in vaccinated mice. Our study is based on our previous model that simulates the cancer - immune System competition activated by a tumor vaccine. In what follows, we show first results on effects of deconstructing the components of Triplex vaccine that are in very good agreement with in vivo results.

Model deconstruction of an immunoprevention vaccine

PAPPALARDO, FRANCESCO;MOTTA, Santo;
2006-01-01

Abstract

We present a further step in developing an in silico model that simulates the immune system responses to tumor cells in vaccinated mice. Our study is based on our previous model that simulates the cancer - immune System competition activated by a tumor vaccine. In what follows, we show first results on effects of deconstructing the components of Triplex vaccine that are in very good agreement with in vivo results.
2006
9783540459071
Mathematical models; Computer simulation
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11769/88955
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