Enhanced expression of PACAP and of its high affinity receptor (PAC1) in the hippocampus and cerebral cortex of dopamine D3 knockout mice.

IJAE Vol . 120, n . 1 (Supplement): 172, 2015 © 2015 Firenze University Press ht tp://www.fupress.com/ijae ITALIAN JOURNAL OF ANATOMY AND EMBRYOLOGY Enhanced expression of PACAP and of its high affinity receptor (PAC1) in the hippocampus and cerebral cortex of dopamine D3 knockout mice Rubina Marzagalli1, Rosa Imbesi1, Venera Mazzone2, Gian Marco Leggio3, Kevin Keay4, Alessandro Castorina1 1 Section of Human Anatomy and Histology - Department of Biomedical Sciences and Biotechnologies, University of Catania, Catania, Italy - 2 Section of Anatomy - Department of Medical, Surgical Sciences and Advanced Technologies, University of Catania, Catania, Italy - 3 Section of Pharmacology - Department of Biomedical Sciences and Biotechnologies, University of Catania, Catania, Italy - 4 Discipline of Anatomy and Histology - School of Medical Sciences, Anderson Stuart Building / University of Sydney, Sydney, NSW, Australia Dopamine (DA) D3 receptor (D3R) is a pre-synaptic autoreceptor whose main role is to modulate DA re