Formation of the domain structures in l,2-dipalmitoyl-sn-glycero-3-phosphoholine (DPPC) mixtures with lipids has been investigated. The influence of sphingomyelin (SM), cholesterol (CHL) and quercetin-3-O-palmitate (Q3P) additives on film properties has been studied. Homogeneous film formation, filament structures and solid domains existence have been found by AFM in monomolecular Langmuir-Blodgett films depending on the ratios of lipids. In particular, formation of small domains in three components DPPC:SM:CHL monolayer has been confirmed by AFM at low concentration of CHL (less a 10% molar).
LB Films based on Phospholipids: Self-Organization and Domain Formation
MARLETTA, Giovanni
2009-01-01
Abstract
Formation of the domain structures in l,2-dipalmitoyl-sn-glycero-3-phosphoholine (DPPC) mixtures with lipids has been investigated. The influence of sphingomyelin (SM), cholesterol (CHL) and quercetin-3-O-palmitate (Q3P) additives on film properties has been studied. Homogeneous film formation, filament structures and solid domains existence have been found by AFM in monomolecular Langmuir-Blodgett films depending on the ratios of lipids. In particular, formation of small domains in three components DPPC:SM:CHL monolayer has been confirmed by AFM at low concentration of CHL (less a 10% molar).File in questo prodotto:
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