AMATA, EMANUELE
AMATA, EMANUELE
SCIENZE DEL FARMACO E DELLA SALUTE (DSFS) (Department of Drug and Health Sciences)
(+)-and (−)-Phenazocine enantiomers: evaluation of their dual opioid agonist/σ1 antagonist properties and antinociceptive effects
2017-01-01 Prezzavento, Orazio; Arena, Emanuela; Sánchez-Fernández, Cristine; Turnaturi, Rita; Parenti, Carmela; Marrazzo, Agostino; Catalano, Roberto; Amata, Emanuele; Pasquinucci, Lorella; Cobos J., Enrique
(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties
2018-01-01 Amata, Emanuele; Rescifina, Antonio; Prezzavento, Orazio; Arena, Emanuela; Dichiara, Maria; Pittalà, Valeria; Montilla-Garcia, A ngeles; Punzo, Francesco; Merino, Pedro; Cobos J., Enrique; Marrazzo, Agostino
4-Nitro-2,1,3-benzoxadiazole derivatives as potential fluorescent sigma receptor probes
2015-01-01 Schininà, Barbara; Martorana, Andrea; Colabufo Nicola, Antonio; Contino, Marialessandra; Niso, Mauro; Perrone Maria, Grazia; DE GUIDI, Guido; Catalfo, Alfio; Rappazzo, Giancarlo; Zuccarello, Elisa; Prezzavento, Orazio; Amata, Emanuele; Rescifina, Antonio; Marrazzo, Agostino
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor
2019-01-01 Romeo, Giuseppe; Salerno, Loredana; Pittalà, Valeria; Candido, Marialuisa; Intagliata, Sebastiano; Amata, Emanuele; Salmona, Mario; Cagnotto, Alfredo; Rescifina, Antonio; Floresta, Giuseppe; Modica, Maria Nunziata
A new Sigma-1 Receptor antagonist in Chronic Pain Treatment: (+)-2R/S-LP2 effects in inflammatory and neuropathic pain
2022-01-01 Spoto, Salvatore; Pasquinucci, Lorella Giuseppina; Turnaturi, Rita; Costanzo, Giuliana; Chiechio, Santina; Vicario, Nunzio; Parenti, Rosalba; Marrazzo, Agostino; Amata, Emanuele; Parenti, Carmela
A pseudouridine isoxazolidinyl nucleoside analogue structural analysis: A morphological approach
2018-01-01 Floresta, Giuseppe; Pistara', Venerando; Christensen E., Kirsten; Amata, Emanuele; Marrazzo, Agostino; Gentile, Davide; Rescifina, Antonio; Punzo, Francesco
A structure-and ligand-based virtual screening of a database of “small” marine natural products for the identification of “blue” sigma-2 receptor ligands
2018-01-01 Floresta, Giuseppe; Amata, Emanuele; Barbaraci, Carla; Gentile, Davide; Turnaturi, Rita; Marrazzo, Agostino; Rescifina, Antonio
Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review
2017-01-01 Floresta, Giuseppe; Pistarà, Venerando; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Prezzavento, Orazio; Rescifina, Antonio
Antiangiogenic Effect of (±)-Haloperidol Metabolite II Valproate Ester [(±)-MRJF22] in Human Microvascular Retinal Endothelial Cells
2016-01-01 Olivieri, Melania; Amata, Emanuele; Vinciguerra, Shila; Fiorito, Jole; Giurdanella, Giovanni; Drago, Filippo; Caporarello, Nunzia; Prezzavento, Orazio; Arena, Emanuela; Salerno, Loredana; Rescifina, Antonio; Lupo, Gabriella; Anfuso, CARMELINA DANIELA; Marrazzo, Agostino
Antioxidant activity of (+)-Pentazocine on activated microglia
file da validare2015-01-01 Marrazzo, Agostino; Heiss, Kathrin; Prezzavento, Orazio; Arena, Emanuela; Amata, Emanuele; LI VOLTI, Giovanni
Antioxidant properties and pharmacokinetic studies of new selective σ1 bifunctional ligands
file da validare2015-01-01 Marrazzo, Agostino; Arena, Emanuela; Cacciatore, Ivana; Cerasa Laura, S.; Amata, Emanuele; Pittala', Valeria; Pasquinucci, Lorella Giuseppina; Turkez, Hasan; Di Stefano, Antonio; Prezzavento, Orazio
Antitrypanosomal lead discovery: Identification of a ligand-efficient inhibitor of Trypanosoma cruzi CYP51 and parasite growth
2013-01-01 Andriani, Grasiella; Amata, Emanuele; Beatty, Joel; Clements, Zeke; Coffey J., Brian; Courtemanche, Gilles; Devine, William; Erath, Jessey; Juda E., Cristin; Wawrzak, Zdzislaw; Wood T., Jodianne; Lepesheva L., Galina; Rodriguez, Ana; Pollastri P., Michael
C-5'-Triazolyl-2'-oxa-3'-aza-4'a-carbanucleosides: Synthesis and biological evaluation
2015-01-01 Romeo, Roberto; Carnovale, Caterina; Giofrè V., Salvatore; Chiacchio, MARIA ASSUNTA ROSSELLA; Garozzo, Adriana; Amata, Emanuele; Romeo, Giovanni; Chiacchio, Ugo
Caspase-3 activation in human melanoma A375 cell line by a novel selective sigma-2 agonist
2016-01-01 Ronsisvalle, Simone; Aricò, Giuseppina; Cova, ANNA MARIA; Blanco, Palma; Amata, Emanuele; Pappalardo, Maria Sebastiana; Pasquinucci, Lorella; Spadaro, Angelo; Ronsisvalle, Nicole
CNS permeability parameters determination through a statistical analysis driven approach
2019-01-01 Dichiara, Maria; Marrazzo, Agostino; Amata, Emanuele
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity
2021-01-01 Romeo, Giuseppe; Ciaffaglione, Valeria; Amata, Emanuele; Dichiara, Maria; Calabrese, Loredana; Vanella, Luca; Sorrenti, Valeria; Grosso, Salvo; D'Amico, AGATA GRAZIA; D'Agata, Velia; Intagliata, Sebastiano; Salerno, Loredana
Composti inorganici [Cap. 6]
2017-01-01 Amata, Emanuele; Dichiara, Maria
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors
2017-01-01 Amata, Emanuele; Marrazzo, Agostino; Dichiara, Maria; Modica, Maria Nunziata; Salerno, Loredana; Prezzavento, Orazio; Nastasi, Giovanni; Rescifina, Antonio; Romeo, Giuseppe; Pittalà, Valeria
Correction to Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents
file da validare2022-01-01 Nicol(`(o)) Fallica, Antonino; Barbaraci, Carla; Amata, Emanuele; Pasquinucci, Lorella; Turnaturi, Rita; Dichiara, Maria; Intagliata, Sebastiano; Bruna Gariboldi, Marzia; Marras, Emanuela; Teresa Orlandi, Viviana; Ferroni, Claudia; Martini, Cecilia; Rescifina, Antonio; Gentile, Davide; Varchi, Greta; Marrazzo, Agostino
Cytotoxicity Profiles and Neuroprotective Properties of the Novel Ifenprodil Analogues as Sigma Ligands
2023-01-01 Zampieri, Daniele; Calabretti, Antonella; Romano, Maurizio; Fortuna, Sara; Collina, Simona; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Mamolo Maria, Grazia
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| (+)-and (−)-Phenazocine enantiomers: evaluation of their dual opioid agonist/σ1 antagonist properties and antinociceptive effects | 1-gen-2017 | Prezzavento, Orazio; Arena, Emanuela; Sánchez-Fernández, Cristine; Turnaturi, Rita; Parenti, Carmela; Marrazzo, Agostino; Catalano, Roberto; Amata, Emanuele; Pasquinucci, Lorella; Cobos J., Enrique | |
| (+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties | 1-gen-2018 | Amata, Emanuele; Rescifina, Antonio; Prezzavento, Orazio; Arena, Emanuela; Dichiara, Maria; Pittalà, Valeria; Montilla-Garcia, A ngeles; Punzo, Francesco; Merino, Pedro; Cobos J., Enrique; Marrazzo, Agostino | |
| 4-Nitro-2,1,3-benzoxadiazole derivatives as potential fluorescent sigma receptor probes | 1-gen-2015 | Schininà, Barbara; Martorana, Andrea; Colabufo Nicola, Antonio; Contino, Marialessandra; Niso, Mauro; Perrone Maria, Grazia; DE GUIDI, Guido; Catalfo, Alfio; Rappazzo, Giancarlo; Zuccarello, Elisa; Prezzavento, Orazio; Amata, Emanuele; Rescifina, Antonio; Marrazzo, Agostino | |
| [1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor | 1-gen-2019 | Romeo, Giuseppe; Salerno, Loredana; Pittalà, Valeria; Candido, Marialuisa; Intagliata, Sebastiano; Amata, Emanuele; Salmona, Mario; Cagnotto, Alfredo; Rescifina, Antonio; Floresta, Giuseppe; Modica, Maria Nunziata | |
| A new Sigma-1 Receptor antagonist in Chronic Pain Treatment: (+)-2R/S-LP2 effects in inflammatory and neuropathic pain | 1-gen-2022 | Spoto, Salvatore; Pasquinucci, Lorella Giuseppina; Turnaturi, Rita; Costanzo, Giuliana; Chiechio, Santina; Vicario, Nunzio; Parenti, Rosalba; Marrazzo, Agostino; Amata, Emanuele; Parenti, Carmela | |
| A pseudouridine isoxazolidinyl nucleoside analogue structural analysis: A morphological approach | 1-gen-2018 | Floresta, Giuseppe; Pistara', Venerando; Christensen E., Kirsten; Amata, Emanuele; Marrazzo, Agostino; Gentile, Davide; Rescifina, Antonio; Punzo, Francesco | |
| A structure-and ligand-based virtual screening of a database of “small” marine natural products for the identification of “blue” sigma-2 receptor ligands | 1-gen-2018 | Floresta, Giuseppe; Amata, Emanuele; Barbaraci, Carla; Gentile, Davide; Turnaturi, Rita; Marrazzo, Agostino; Rescifina, Antonio | |
| Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review | 1-gen-2017 | Floresta, Giuseppe; Pistarà, Venerando; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Prezzavento, Orazio; Rescifina, Antonio | |
| Antiangiogenic Effect of (±)-Haloperidol Metabolite II Valproate Ester [(±)-MRJF22] in Human Microvascular Retinal Endothelial Cells | 1-gen-2016 | Olivieri, Melania; Amata, Emanuele; Vinciguerra, Shila; Fiorito, Jole; Giurdanella, Giovanni; Drago, Filippo; Caporarello, Nunzia; Prezzavento, Orazio; Arena, Emanuela; Salerno, Loredana; Rescifina, Antonio; Lupo, Gabriella; Anfuso, CARMELINA DANIELA; Marrazzo, Agostino | |
| Antioxidant activity of (+)-Pentazocine on activated microglia | 1-gen-2015 | Marrazzo, Agostino; Heiss, Kathrin; Prezzavento, Orazio; Arena, Emanuela; Amata, Emanuele; LI VOLTI, Giovanni | file da validare |
| Antioxidant properties and pharmacokinetic studies of new selective σ1 bifunctional ligands | 1-gen-2015 | Marrazzo, Agostino; Arena, Emanuela; Cacciatore, Ivana; Cerasa Laura, S.; Amata, Emanuele; Pittala', Valeria; Pasquinucci, Lorella Giuseppina; Turkez, Hasan; Di Stefano, Antonio; Prezzavento, Orazio | file da validare |
| Antitrypanosomal lead discovery: Identification of a ligand-efficient inhibitor of Trypanosoma cruzi CYP51 and parasite growth | 1-gen-2013 | Andriani, Grasiella; Amata, Emanuele; Beatty, Joel; Clements, Zeke; Coffey J., Brian; Courtemanche, Gilles; Devine, William; Erath, Jessey; Juda E., Cristin; Wawrzak, Zdzislaw; Wood T., Jodianne; Lepesheva L., Galina; Rodriguez, Ana; Pollastri P., Michael | |
| C-5'-Triazolyl-2'-oxa-3'-aza-4'a-carbanucleosides: Synthesis and biological evaluation | 1-gen-2015 | Romeo, Roberto; Carnovale, Caterina; Giofrè V., Salvatore; Chiacchio, MARIA ASSUNTA ROSSELLA; Garozzo, Adriana; Amata, Emanuele; Romeo, Giovanni; Chiacchio, Ugo | |
| Caspase-3 activation in human melanoma A375 cell line by a novel selective sigma-2 agonist | 1-gen-2016 | Ronsisvalle, Simone; Aricò, Giuseppina; Cova, ANNA MARIA; Blanco, Palma; Amata, Emanuele; Pappalardo, Maria Sebastiana; Pasquinucci, Lorella; Spadaro, Angelo; Ronsisvalle, Nicole | |
| CNS permeability parameters determination through a statistical analysis driven approach | 1-gen-2019 | Dichiara, Maria; Marrazzo, Agostino; Amata, Emanuele | |
| Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity | 1-gen-2021 | Romeo, Giuseppe; Ciaffaglione, Valeria; Amata, Emanuele; Dichiara, Maria; Calabrese, Loredana; Vanella, Luca; Sorrenti, Valeria; Grosso, Salvo; D'Amico, AGATA GRAZIA; D'Agata, Velia; Intagliata, Sebastiano; Salerno, Loredana | |
| Composti inorganici [Cap. 6] | 1-gen-2017 | Amata, Emanuele; Dichiara, Maria | |
| Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors | 1-gen-2017 | Amata, Emanuele; Marrazzo, Agostino; Dichiara, Maria; Modica, Maria Nunziata; Salerno, Loredana; Prezzavento, Orazio; Nastasi, Giovanni; Rescifina, Antonio; Romeo, Giuseppe; Pittalà, Valeria | |
| Correction to Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents | 1-gen-2022 | Nicol(`(o)) Fallica, Antonino; Barbaraci, Carla; Amata, Emanuele; Pasquinucci, Lorella; Turnaturi, Rita; Dichiara, Maria; Intagliata, Sebastiano; Bruna Gariboldi, Marzia; Marras, Emanuela; Teresa Orlandi, Viviana; Ferroni, Claudia; Martini, Cecilia; Rescifina, Antonio; Gentile, Davide; Varchi, Greta; Marrazzo, Agostino | file da validare |
| Cytotoxicity Profiles and Neuroprotective Properties of the Novel Ifenprodil Analogues as Sigma Ligands | 1-gen-2023 | Zampieri, Daniele; Calabretti, Antonella; Romano, Maurizio; Fortuna, Sara; Collina, Simona; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Mamolo Maria, Grazia |