| Nome |
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Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells, file 764778a8-4820-427c-a4ac-0a61a51cc6b3
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88
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Nanotechnological Approach to Increase the Antioxidant and Cytotoxic Efficacy of Crocin and Crocetin, file dfe4d22a-1b95-bb0a-e053-d805fe0a78d9
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23
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Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors, file dfe4d228-8414-bb0a-e053-d805fe0a78d9
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21
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Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats, file dfe4d22b-ca6c-bb0a-e053-d805fe0a78d9
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17
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Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity, file dfe4d22e-96aa-bb0a-e053-d805fe0a78d9
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16
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Rescuing Abandoned Molecules as Nav1.7 and
PCSK9 Inhibitors, file dfe4d227-15a3-bb0a-e053-d805fe0a78d9
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13
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In vitro antioxidant activity of idebenone derivative-loaded solid lipid nanoparticles, file dfe4d227-df53-bb0a-e053-d805fe0a78d9
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13
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Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death, file dfe4d22b-64a8-bb0a-e053-d805fe0a78d9
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12
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Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate, file dfe4d22e-7c6a-bb0a-e053-d805fe0a78d9
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12
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Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation, file dfe4d228-fcaa-bb0a-e053-d805fe0a78d9
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11
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Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia, file 063124c7-5567-4085-b223-1475db6dcb7b
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10
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Effects of Novel Nitric Oxide-Releasing Molecules against Oxidative Stress on Retinal Pigmented Epithelial Cells, file dfe4d228-b056-bb0a-e053-d805fe0a78d9
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10
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Synthesis and experimental validation of new designed heterocyclic compounds with antiproliferative activity versus breast cancer cell lines MCF-7 and MDA-MB-231, file dfe4d228-a89f-bb0a-e053-d805fe0a78d9
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9
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Novel mutual prodrug of 5-fluorouracil and heme oxygenase-1 inhibitor (5-FU/HO-1 hybrid): design and preliminary in vitro evaluation, file dfe4d22e-9b9b-bb0a-e053-d805fe0a78d9
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9
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Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts, file dfe4d228-b7ff-bb0a-e053-d805fe0a78d9
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8
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Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity, file e783310a-abb7-48b9-80da-e4114feef75c
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8
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On the reaction between 3-bromo-2-nitrobenzo[b]thiophene and some amines: a novel aromatic nucleophilic substitution with rearrangement, file dfe4d227-1637-bb0a-e053-d805fe0a78d9
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7
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Simultaneus Determination of Catechins, Rutin, and Gallic Acid in Cistus Species Extracts by HPLC with Diode Array Detection, file dfe4d227-3e27-bb0a-e053-d805fe0a78d9
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6
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Synthesis and receptor binding of new thieno[2,3-d]pyrimidines as selective ligands of 5-HT3 receptors, file dfe4d228-c0f3-bb0a-e053-d805fe0a78d9
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6
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Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products, file dfe4d229-932b-bb0a-e053-d805fe0a78d9
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6
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New arylethanolimidazole derivatives as HO-1 inhibitors with cytotoxicity against MCF-7 breast cancer cells, file dfe4d22b-f8b7-bb0a-e053-d805fe0a78d9
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6
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Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells, file c4467edb-68a4-4e61-8ef1-53c053dbaea0
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5
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Evaluation of Imidazole-Based Compounds as
Heme Oxygenase-1 Inhibitors, file dfe4d227-09cd-bb0a-e053-d805fe0a78d9
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5
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How does binding of imidazole-based inhibitors to heme
oxygenase-1 influence their conformation? Insights
combining crystal structures and molecular modelling, file dfe4d227-3fc2-bb0a-e053-d805fe0a78d9
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5
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Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands, file dfe4d229-a928-bb0a-e053-d805fe0a78d9
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5
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The Inhibition of Neuropathic Pain Incited by Nerve Injury and Accompanying Mood Disorders by New Heme Oxygenase-1 Inducers: Mechanisms Implicated, file 9f3ee61e-f877-4476-bd40-5f2c34fb96b5
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4
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Antiangiogenic Effect of (±)-Haloperidol Metabolite II Valproate Ester [(±)-MRJF22] in Human Microvascular Retinal Endothelial Cells, file dfe4d227-1ce5-bb0a-e053-d805fe0a78d9
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4
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Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides, file dfe4d227-4717-bb0a-e053-d805fe0a78d9
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4
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Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors, file dfe4d228-8ada-bb0a-e053-d805fe0a78d9
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4
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Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia, file dfe4d228-a89c-bb0a-e053-d805fe0a78d9
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4
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Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands, file dfe4d22b-a0bb-bb0a-e053-d805fe0a78d9
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4
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Novel heme oxygenase-1 (Ho-1) inducers based on dimethyl fumarate structure, file dfe4d22d-ff3a-bb0a-e053-d805fe0a78d9
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4
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Potential health benefits of a pomegranate extract, rich in phenolic com-pounds, in intestinal inflammation, file dfe4d22e-7839-bb0a-e053-d805fe0a78d9
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4
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In vitro and in silico analysis of imatinib analogues as anti- Trypanosoma cruzi drug candidates, file 05cbf279-c77b-4688-ac56-834a1c8918d6
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3
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An alpha1-adrenergic receptor ligand repurposed as a
potent antiproliferative agent for head and neck
squamous cell carcinoma, file dfe4d227-2aac-bb0a-e053-d805fe0a78d9
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3
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Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells, file dfe4d228-83c2-bb0a-e053-d805fe0a78d9
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3
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Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis, file dfe4d229-5824-bb0a-e053-d805fe0a78d9
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3
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Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines, file dfe4d229-5b0e-bb0a-e053-d805fe0a78d9
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3
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Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions, file dfe4d229-9975-bb0a-e053-d805fe0a78d9
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3
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Heme Oxygenase Inhibition Sensitizes Neuroblastoma Cells to Carfilzomib, file dfe4d22a-159f-bb0a-e053-d805fe0a78d9
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3
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Progress in the development of more effective and safer analgesics for pain management, file dfe4d22a-f2ae-bb0a-e053-d805fe0a78d9
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3
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Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-1, file dfe4d22b-1138-bb0a-e053-d805fe0a78d9
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3
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Therapeutic Potential of Caffeic Acid Phenethyl Ester (CAPE) in Diabetes., file dfe4d22b-54ea-bb0a-e053-d805fe0a78d9
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3
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Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents, file dfe4d22b-b25d-bb0a-e053-d805fe0a78d9
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3
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Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinolinecarboxylic acid derivatives, file 981a7929-2787-49b9-8be7-468edebf6bcd
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2
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CAPE and its synthetic derivative VP961 restore BACH1/NRF2 axis in Down Syndrome, file b1cf3d6b-f092-49ed-8f8e-c83e88b074a7
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2
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New N- and O-arylpiperazinylalkyl pyrimidines and
2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands:
Synthesis, structure-activity relationships, and molecular modeling
studies, file dfe4d227-15bf-bb0a-e053-d805fe0a78d9
|
2
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High affinity ligands and potent antagonists for the alpha1D-adrenergic
receptor. Novel 3,8-disubstituted [1]benzothieno[3,2-d]pyrimidine
derivatives, file dfe4d227-1e4b-bb0a-e053-d805fe0a78d9
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2
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NOVEL ANTAGONISTS FOR alha1-ADRENOCEPTOR SUBTYPES, file dfe4d227-1e96-bb0a-e053-d805fe0a78d9
|
2
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Structure-activity relationships and molecular modeling studies of
novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones
as 5-HT7 and 5-HT1A receptor ligands, file dfe4d227-2139-bb0a-e053-d805fe0a78d9
|
2
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Synthesis and Biological Activity of 1-, 2- or 3-Substituted Benzothieno[2,3-d]triazole Derivatives Structurally related to Trazodone., file dfe4d227-26d9-bb0a-e053-d805fe0a78d9
|
2
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3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands, file dfe4d228-bcfc-bb0a-e053-d805fe0a78d9
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2
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Novel inhibitors of neuronal nitric oxide synthase, file dfe4d228-bf9b-bb0a-e053-d805fe0a78d9
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2
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Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors, file dfe4d229-0a66-bb0a-e053-d805fe0a78d9
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2
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Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application, file dfe4d229-892f-bb0a-e053-d805fe0a78d9
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2
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Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers, file dfe4d22a-8975-bb0a-e053-d805fe0a78d9
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2
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Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors, file dfe4d22b-0e1f-bb0a-e053-d805fe0a78d9
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2
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Ginseng and heme oxygenase-1: The link between an old herb and a new protective system, file dfe4d22b-2737-bb0a-e053-d805fe0a78d9
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2
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Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update, file dfe4d22b-d5ff-bb0a-e053-d805fe0a78d9
|
2
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Growing the molecular architecture of imidazole-like ligands in HO-1 complexes, file dfe4d22e-7c94-bb0a-e053-d805fe0a78d9
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2
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Novel Heme Oxygenase-1 Inducers Palliate Inflammatory Pain and Emotional Disorders by Regulating NLRP3 Inflammasome and Activating the Antioxidant Pathway, file 0a900c8d-c2d0-45a7-a880-4969c718fd39
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1
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Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists, file af56fd43-07a1-4236-ad34-51fe9af5fc09
|
1
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|
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands, file dfe4d226-f833-bb0a-e053-d805fe0a78d9
|
1
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New Pyrimido[5,4-b]indoles and [1]Benzothieno[3,2-d]pyrimidines. High Affinity Ligands for the a 1 - Adrenoceptor Subtypes, file dfe4d226-f983-bb0a-e053-d805fe0a78d9
|
1
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Imidazole derivatives as antioxidants and selective inhibitors of nNOS, file dfe4d226-fad6-bb0a-e053-d805fe0a78d9
|
1
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Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years, file dfe4d226-fbc1-bb0a-e053-d805fe0a78d9
|
1
|
|
Synthesis and binding properties of new long-chain 4-substituted piperazine derivatives as 5-HT1A and 5-HT7 receptor ligands, file dfe4d226-fdeb-bb0a-e053-d805fe0a78d9
|
1
|
|
Novel imidazole derivatives as heme oxygenase-1 (HO-1) and heme oxygenase-2 (HO-2) inhibitors and their cytotoxic activity in human-derived cancer cell lines, file dfe4d226-fe61-bb0a-e053-d805fe0a78d9
|
1
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Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives, file dfe4d227-00ef-bb0a-e053-d805fe0a78d9
|
1
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Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands, file dfe4d227-0101-bb0a-e053-d805fe0a78d9
|
1
|
|
Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for alpha1-adrenoceptor subtypes., file dfe4d227-0857-bb0a-e053-d805fe0a78d9
|
1
|
|
Novel inhibitors of nitric oxide synthase with antioxidant properties, file dfe4d227-096a-bb0a-e053-d805fe0a78d9
|
1
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|
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS, file dfe4d227-0a94-bb0a-e053-d805fe0a78d9
|
1
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A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands, file dfe4d227-0e6d-bb0a-e053-d805fe0a78d9
|
1
|
|
Design and synthesis of new homo and hetero bis-piperazinyl-1-
propanone derivatives as 5-HT7R selective ligands over 5-HT1AR, file dfe4d227-15a5-bb0a-e053-d805fe0a78d9
|
1
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N-subsituted imidazoles as inhibitors of nitric oxide synthase: a preliminary screening, file dfe4d227-1ae0-bb0a-e053-d805fe0a78d9
|
1
|
|
1-[(aryloxy)alkyl]-1H-imidazoles as inhibitors of neuronal nitric oxide synthase., file dfe4d227-22d4-bb0a-e053-d805fe0a78d9
|
1
|
|
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes, file dfe4d227-41e9-bb0a-e053-d805fe0a78d9
|
1
|
|
New compounds controlling NO overproduction, file dfe4d227-939f-bb0a-e053-d805fe0a78d9
|
1
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New compounds controlling NO overproduction, file dfe4d227-93a0-bb0a-e053-d805fe0a78d9
|
1
|
|
Recent advances in drug discovery of phototherapeutic non-porphyrinic anticancer agents, file dfe4d228-7eb8-bb0a-e053-d805fe0a78d9
|
1
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|
Novel selective ligands for the serotonergic 5-HT7 receptor: tricyclic derivatives Bearing the pyrimido-4(3H)-one ring, file dfe4d228-83c7-bb0a-e053-d805fe0a78d9
|
1
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Role of the Nrf2/HO-1 axis in bronchopulmonary dysplasia and hyperoxic lung injuries, file dfe4d228-8416-bb0a-e053-d805fe0a78d9
|
1
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Heme Oxygenase-1 Inhibition: A Novel Strategy for the Design of Azole-Based Antitumour Agents, file dfe4d228-8432-bb0a-e053-d805fe0a78d9
|
1
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Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor, file dfe4d228-8440-bb0a-e053-d805fe0a78d9
|
1
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Targeting Heme Oxygenase-1 to Overcome Imatinib Resistance in Chronic Myeloid Leukemia, file dfe4d228-8442-bb0a-e053-d805fe0a78d9
|
1
|
|
Novel (E)-alpha-[(1H-indol-3-yl)methylene]benzeneacetic Acids as Endothelin Receptor Ligands., file dfe4d228-b50b-bb0a-e053-d805fe0a78d9
|
1
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Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor, file dfe4d228-b517-bb0a-e053-d805fe0a78d9
|
1
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[1,2,4]Triazole derivatives as 5-HT1A serotonin receptor ligands, file dfe4d228-b51c-bb0a-e053-d805fe0a78d9
|
1
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PROGRESS IN THE DEVELOPMENT OF SELECTIVE NITRIC OXIDE SYNTHASE (NOS) INHIBITORS, file dfe4d228-b51f-bb0a-e053-d805fe0a78d9
|
1
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5-HT7 receptor ligands: recent developments and potential therapeutic applications, file dfe4d228-b6a0-bb0a-e053-d805fe0a78d9
|
1
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A focus on Heme Oxygenase-1 (HO-1) inhibitors, file dfe4d228-bade-bb0a-e053-d805fe0a78d9
|
1
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Inhibition of Neuronal Nitric Oxide Synthase by N-Phenacyl Imidazoles, file dfe4d228-baea-bb0a-e053-d805fe0a78d9
|
1
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Transport of alpha-tocopherol and its derivatives through erythrocyte membranes, file dfe4d228-baed-bb0a-e053-d805fe0a78d9
|
1
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Synthesis and molecular modeling of 1H-pyrrolopyrimidine-2,4-dione derivatives as ligands for the alpha1-adrenoceptors, file dfe4d228-bb52-bb0a-e053-d805fe0a78d9
|
1
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Synthesis and Binding Properties of New Endothelin Receptor Ligands, file dfe4d228-bc7d-bb0a-e053-d805fe0a78d9
|
1
|
|
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation, file dfe4d228-bd1b-bb0a-e053-d805fe0a78d9
|
1
|
|
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors, file dfe4d228-bf52-bb0a-e053-d805fe0a78d9
|
1
|
|
Synthesis of novel 4,5-diphenylthiazole derivatives as potential acylCoA:cholesterol O-acyltransferase inhibitors, file dfe4d228-bf58-bb0a-e053-d805fe0a78d9
|
1
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New homo and hetero bis-arylpiperazine and bis-benzylpiperazine derivatives as 5-HT7R selective ligands: design and synthesis, file dfe4d229-0a63-bb0a-e053-d805fe0a78d9
|
1
|
| Totale |
468 |