| Nome |
# |
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Targeting the Cancer Initiating Cell: The Ultimate Target for Cancer Therapy, file dfe4d227-957b-bb0a-e053-d805fe0a78d9
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1.041
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Immunoexpression and localization of heme-oxygenase-1 and MIF in lung exposed to asbestos-like fibers: an in vivo study, file dfe4d22b-26f9-bb0a-e053-d805fe0a78d9
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245
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MFP14, a multifunctional emerging protein with immunomodulatory properties, prevents spontaneous and recurrent autoimmune diabetes in NOD mice, file dfe4d227-1ab0-bb0a-e053-d805fe0a78d9
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195
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HIV-protease inhibitors for the treatment of cancer: Repositioning HIV protease inhibitors while developing more potent NO-hybridized derivatives?, file dfe4d22b-7950-bb0a-e053-d805fe0a78d9
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129
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Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine, file dfe4d226-f3f8-bb0a-e053-d805fe0a78d9
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91
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Identification of CD4+ T cell biomarkers for predicting the response of patients with relapsing-remitting multiple sclerosis to natalizumab treatment, file dfe4d22b-7945-bb0a-e053-d805fe0a78d9
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32
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Effects of mutations in Wnt/β-catenin, hedgehog, Notch and PI3K pathways on GSK-3 activity-Diverse effects on cell growth, metabolism and cancer., file dfe4d22b-ba7f-bb0a-e053-d805fe0a78d9
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28
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Characterization of the pathophysiological role of CD47 in uveal melanoma, file dfe4d229-e2cb-bb0a-e053-d805fe0a78d9
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24
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Identification of novel chemotherapeutic strategies for metastatic uveal melanoma, file dfe4d22a-c240-bb0a-e053-d805fe0a78d9
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23
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Contribution of the macrophage migration inhibitory factor superfamily of cytokines in the pathogenesis of preclinical and human multiple sclerosis: In silico and in vivo evidences, file dfe4d22b-935f-bb0a-e053-d805fe0a78d9
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22
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Acquired Immune Resistance Follows Complete Tumor Regression without Loss of Target Antigens or IFNγ Signaling., file dfe4d22b-7609-bb0a-e053-d805fe0a78d9
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20
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Aberrant Expression of MHC Class II in Melanoma Attracts Inflammatory Tumor-Specific CD4+ T- Cells, Which Dampen CD8+ T-cell Antitumor Reactivity., file dfe4d22b-7c67-bb0a-e053-d805fe0a78d9
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20
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Evaluation of hyaluronic acid-P40 conjugated cream in a mouse model of dermatitis induced by oxazolone, file dfe4d22d-2a55-bb0a-e053-d805fe0a78d9
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19
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Anti-angiogenic Therapy in Cancer: Downsides and New Pivots for Precision Medicine, file dfe4d227-b49c-bb0a-e053-d805fe0a78d9
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17
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Differential modulation and prognostic values of immune-escape genes in uveal melanoma, file dfe4d229-e6c3-bb0a-e053-d805fe0a78d9
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17
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Overexpression of macrophage migration inhibitory factor and functionally‑related genes, D‑DT, CD74, CD44, CXCR2 and CXCR4, in glioblastoma, file dfe4d22b-9bdc-bb0a-e053-d805fe0a78d9
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17
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KCNMA1 Expression is Downregulated in Colorectal Cancer via Epigenetic Mechanisms, file dfe4d229-8cb8-bb0a-e053-d805fe0a78d9
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16
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Immunobiology of Uveal Melanoma: State of the Art and Therapeutic Targets, file dfe4d229-e265-bb0a-e053-d805fe0a78d9
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15
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The H2S Donor GYY4137 Stimulates Reactive Oxygen Species Generation in BV2 Cells While Suppressing the Secretion of TNF and Nitric Oxide, file dfe4d22b-5bdb-bb0a-e053-d805fe0a78d9
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15
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Characterization of Altered Molecular Pathways in the Entorhinal Cortex of Alzheimer's Disease Patients and In Silico Prediction of Potential Repurposable Drugs, file e45f3106-9a74-4b42-8af7-03a25e8091d8
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15
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Decitabine induces regulatory T cells, inhibits the production of IFN-gamma and IL-17 and exerts preventive and therapeutic efficacy in rodent experimental autoimmune neuritis, file dfe4d22b-7944-bb0a-e053-d805fe0a78d9
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14
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Anticancer and differentiation properties of the nitric oxide derivative of lopinavir in human glioblastoma cells, file dfe4d22b-5bd2-bb0a-e053-d805fe0a78d9
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13
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The role of macrophages in neuroinflammatory and neurodegenerative pathways of alzheimer’s disease, amyotrophic lateral sclerosis, and multiple sclerosis: Pathogenetic cellular effectors and potential therapeutic targets, file dfe4d22b-64a9-bb0a-e053-d805fe0a78d9
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13
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Pathogenic role for macrophage migration inhibitory factor in glioblastoma and its targeting with specific inhibitors as novel tailored therapeutic approach., file dfe4d22b-b387-bb0a-e053-d805fe0a78d9
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13
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Computational modeling of PI3K/AKT and MAPK signaling pathways in melanoma cancer, file dfe4d227-7fdf-bb0a-e053-d805fe0a78d9
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12
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Preclinical evaluation of the PI3K/Akt/mTOR pathway in animal models of multiple sclerosis, file dfe4d22b-5cfb-bb0a-e053-d805fe0a78d9
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12
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Prediction of PD‐l1 expression in neuroblastoma via computational modeling, file dfe4d22b-88bb-bb0a-e053-d805fe0a78d9
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12
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Vitamin D3: a helpful immuno-modulator, file dfe4d227-0c89-bb0a-e053-d805fe0a78d9
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11
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The immunobiology of apotransferrin in type 1 diabetes, file dfe4d227-34b3-bb0a-e053-d805fe0a78d9
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11
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Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance., file dfe4d227-38b3-bb0a-e053-d805fe0a78d9
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11
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Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response, file dfe4d227-3df4-bb0a-e053-d805fe0a78d9
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11
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Unique antineoplastic profile of Saquinavir-NO, a novel NO-derivative of the protease inhibitor Saquinavir, on the in vitro and in vivo tumor formation of A375 human melanoma cells, file dfe4d227-41e2-bb0a-e053-d805fe0a78d9
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11
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PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approaches, file dfe4d227-9c44-bb0a-e053-d805fe0a78d9
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11
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Anticancer properties of the novel nitric oxide-donating compound (S,R)-3-phenyl-4,5-dihydro-5-isoxazole acetic acid-nitric oxide in vitro and in vivo, file dfe4d226-feb1-bb0a-e053-d805fe0a78d9
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10
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Critical role of macrophage migration inhibitory factor activity in experimental autoimmune diabetes, file dfe4d227-1349-bb0a-e053-d805fe0a78d9
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10
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Ageing: from inflammation to cancer., file dfe4d228-b156-bb0a-e053-d805fe0a78d9
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10
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Transcriptomic analysis reveals involvement of the macrophage migration inhibitory factor gene network in duchenne muscular dystrophy, file dfe4d22b-8465-bb0a-e053-d805fe0a78d9
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10
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Overexpression of macrophage migration inhibitory factor and its homologue d-dopachrome tautomerase as negative prognostic factor in neuroblastoma, file dfe4d22b-8467-bb0a-e053-d805fe0a78d9
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10
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Effects of the immunomodulator, VGX-1027, in endotoxin-induced uveitis in Lewis rats, file dfe4d227-2a6f-bb0a-e053-d805fe0a78d9
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9
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16alpha-Bromoepiandrosterone (HE2000) limits non-productive inflammation and stimulates immunity in lungs, file dfe4d227-3e08-bb0a-e053-d805fe0a78d9
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9
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Effects of Synthetic Anti-Inflammatory Sterol in CB3V-Induced Myocarditis: A Morphological Study on Heart Muscle Tissue, file dfe4d227-4389-bb0a-e053-d805fe0a78d9
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9
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No-Modified Saquinavir is Equally Efficient Against Doxorubicin Sensitive and Resistant Non-Small Cell Lung Carcinoma Cells/MODIFIKOVANA KOVANA FORMA SAKVINAVIRA EFIKASNO SU PRIMI RA RAST ĆELIJA NESITNOĆELIJSKOG KARCINOMA PLUĆA RAZLIČITE OSETUIVOSTI NA DOKSORUBICIN, file dfe4d227-71f6-bb0a-e053-d805fe0a78d9
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9
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Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs, file dfe4d22b-8721-bb0a-e053-d805fe0a78d9
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9
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17α-Ethynyl-androst-5-ene-3β,7β,17β-triol (HE3286) Is Neuroprotective and Reduces Motor Impairment and Neuroinflammation in a Murine MPTP Model of Parkinson's Disease, file dfe4d227-0490-bb0a-e053-d805fe0a78d9
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8
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Phase II study of the antiretroviral activity and safety of the glucocorticoid receptor antagonist mifepristone in HIV-1-infected patients, file dfe4d227-1038-bb0a-e053-d805fe0a78d9
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8
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The Therapeutic Potential of mTOR Inhibitors in Breast Cancer, file dfe4d227-158a-bb0a-e053-d805fe0a78d9
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8
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Blood levels of transforming growth factor-beta 1 (TGF-beta 1) are elevated in both relapsing remitting and chronic progressive multiple sclerosis (MS) patients and are further augmented by treatment with interferon-beta 1b (IFN-beta 1b), file dfe4d227-279b-bb0a-e053-d805fe0a78d9
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8
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Upregulated expression of macrophage migration inhibitory factor, its analogue d-dopachrome tautomerase, and the cd44 receptor in peripheral cd4 t cells from clinically isolated syndrome patients with rapid conversion to clinical defined multiple sclerosis, file dfe4d22b-6ebf-bb0a-e053-d805fe0a78d9
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8
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Effects of combined admistration of imatinib and sorafenib in a murine model of liver fibrosis, file 205387dd-34da-45b8-a709-4620d9f53b7d
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7
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Variable effects of cyclophosphamide in rodent models of experimental allergic encephalomyelitis, file dfe4d226-fc53-bb0a-e053-d805fe0a78d9
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7
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The antitumor properties of a nontoxic, nitric oxide-modified version of saquinavir are independent of Akt, file dfe4d227-0adf-bb0a-e053-d805fe0a78d9
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7
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Involvement of Akt-1 and mTOR in Sensitivity of Breast Cancer to Targeted Therapy, file dfe4d227-0c2c-bb0a-e053-d805fe0a78d9
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7
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Exploiting p53 Status to Enhance Effectiveness of Chemotherapy by Lowering Associated Toxicity, file dfe4d227-103a-bb0a-e053-d805fe0a78d9
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7
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Dominant roles of the Raf/MEK/ERK pathway in cell cycle progression, prevention of apoptosis and sensitivity to chemotherapeutic drugs, file dfe4d227-11b0-bb0a-e053-d805fe0a78d9
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7
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Oral Delivery of Particulate Transforming Growth Factor Beta 1 and All-Trans Retinoic Acid Reduces Gut Inflammation in Murine Models of Inflammatory Bowel Disease, file dfe4d227-8c13-bb0a-e053-d805fe0a78d9
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7
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Effects of NO-Hybridization on the Immunomodulatory Properties of the HIV Protease Inhibitors Lopinavir and Ritonavir., file dfe4d227-8fe8-bb0a-e053-d805fe0a78d9
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7
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Saquinavir-NO inhibits IL-6 production in macrophages, file dfe4d227-a9be-bb0a-e053-d805fe0a78d9
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7
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Emerging role of the macrophage migration inhibitory factor family of cytokines in neuroblastoma. Pathogenic effectors and novel therapeutic targets?, file dfe4d22b-6ec5-bb0a-e053-d805fe0a78d9
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7
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Modulation of tetraspanin 32 (TSPAN32) expression in T cell-mediated immune responses and in multiple sclerosis, file dfe4d22b-8461-bb0a-e053-d805fe0a78d9
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7
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Effects of treatment with the hypomethylating agent 5-aza-2’-deoxycytidine in murine type ii collagen-induced arthritis, file dfe4d22b-8463-bb0a-e053-d805fe0a78d9
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7
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|
The role of macrophage migration inhibitory factor in Alzheimer′s disease: Conventionally pathogenetic or unconventionally protective?, file 112be4d2-0819-44c2-bde5-044b5c2b44ba
|
6
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|
The second-to-fourth digit ratio correlates with the rate of academic performance in medical school students, file dfe4d226-f404-bb0a-e053-d805fe0a78d9
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6
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Prevalence of hepatitis C virus infection among health-care workers: A 10-year survey, file dfe4d226-f7a4-bb0a-e053-d805fe0a78d9
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6
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Identification of novel targets for the diagnosis and treatment of liver fibrosis., file dfe4d227-0529-bb0a-e053-d805fe0a78d9
|
6
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Involvement of Akt and mTOR in chemotherapeutic and hormonal-based drug resistance and response to radiation in breast cancer cells, file dfe4d227-0c2a-bb0a-e053-d805fe0a78d9
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6
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|
The Raf/MEK/ERK pathway can govern drug resistance, apoptosis and sensitivity to targeted therapy, file dfe4d227-120c-bb0a-e053-d805fe0a78d9
|
6
|
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GSK-3 as potential
target for therapeutic intervention in cancer, file dfe4d227-2135-bb0a-e053-d805fe0a78d9
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6
|
|
Therapeutic potential of carbon monoxide in multiple sclerosis, file dfe4d227-390e-bb0a-e053-d805fe0a78d9
|
6
|
|
HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression, file dfe4d227-3953-bb0a-e053-d805fe0a78d9
|
6
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|
In vitro and in vivo anticancer action of Saquinavir-NO, a novel nitric oxide-derivative of the protease inhibitor saquinavir, on hormone resistant prostate cancer cells, file dfe4d227-490f-bb0a-e053-d805fe0a78d9
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6
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|
Profiling of inhibitory immune checkpoints in glioblastoma: Potential pathogenetic players, file dfe4d22d-8847-bb0a-e053-d805fe0a78d9
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6
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|
Transcriptomic data analysis reveals a down-expression of galectin-8 in schizophrenia hippocampus, file dfe4d22e-93a0-bb0a-e053-d805fe0a78d9
|
6
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Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health, file 0b74cc4e-62ac-4aff-bf92-0afc88ddd06d
|
5
|
|
Impaired expression of tetraspanin 32 (TSPAN32) in memory T cells of patients with multiple sclerosis, file 24960f99-878b-4aad-b9b9-1ef2ec2f6af5
|
5
|
|
In silico and in vivo analysis of IL37 in multiple sclerosis reveals its probable homeostatic role on the clinical activity, disability, and treatment with fingolimod, file 3e3ddb0a-a43d-47a5-9e13-836fd9ac225b
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5
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|
Transcriptional upregulation of galectin-3 in multiple sclerosis, file 7850e9ee-d0a3-47aa-9013-2e0a6a51443a
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5
|
|
Macrophage Migration Inhibitory Factor (MIF) and Its Homologue d-Dopachrome Tautomerase (DDT) Inversely Correlate with Inflammation in Discoid Lupus Erythematosus, file ce10a7da-d02e-4388-ab78-cbc4048d53ed
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5
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|
Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy, file dfe4d226-f9e9-bb0a-e053-d805fe0a78d9
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5
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5-androstenediol ameliorates pleurisy, septic shock, and experimental autoimmune encephalomyelitis in mice., file dfe4d227-07a6-bb0a-e053-d805fe0a78d9
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5
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|
Early prophylaxis with recombinant human interleukin-11 prevents spontaneous diabetes in NOD mice, file dfe4d227-0b85-bb0a-e053-d805fe0a78d9
|
5
|
|
Extrahepatic disorders of HCV infection: A distinct entity of B-cell neoplasia?, file dfe4d227-1141-bb0a-e053-d805fe0a78d9
|
5
|
|
An imidazoline compound completely counteracts interleukin-1 [beta] toxic effects to rat pancreatic islet [beta] cells, file dfe4d227-1ab1-bb0a-e053-d805fe0a78d9
|
5
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|
. Autoimmune thyroid disease induced by thyroglobulin and lipopolysaccharide is inhibited by soluble TNF receptor type 1, file dfe4d227-1b2a-bb0a-e053-d805fe0a78d9
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5
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|
Anticancer effects of the nitric oxide-modified saquinavir derivative saquinavir-NO against multidrug-resistant cancer cells, file dfe4d227-1e15-bb0a-e053-d805fe0a78d9
|
5
|
|
Modulation of heat shock proteins during macrophage differentiation., file dfe4d227-3a9b-bb0a-e053-d805fe0a78d9
|
5
|
|
ISO-1 Binding to the Tautomerase Active Site of MIF Inhibits Its Pro-inflammatory Activity and Increases Survival in Severe Sepsis, file dfe4d227-3b57-bb0a-e053-d805fe0a78d9
|
5
|
|
Sex hormones modulate brain damage in multiple sclerosis: MRI evidence, file dfe4d227-3be4-bb0a-e053-d805fe0a78d9
|
5
|
|
Crude extract of hydatid laminated layer from Echinococcus granulosus cyst attenuates mucosal intestinal damage and inflammatory responses in Dextran Sulfate Sodium induced colitis in mice., file dfe4d227-3fc6-bb0a-e053-d805fe0a78d9
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5
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|
Extracellular lysosome-associated membrane protein-1 (LAMP-1) mediates autoimmune disease progression in the NOD model of type 1 diabetes, file dfe4d227-4099-bb0a-e053-d805fe0a78d9
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5
|
|
Combination of cyclophosphamide and interferon-β halts progression in patients with rapidly transitional multiple sclerosis, file dfe4d227-46b8-bb0a-e053-d805fe0a78d9
|
5
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|
Emerging therapeutic targets for the treatment of hepatic fibrosis, file dfe4d227-a0ec-bb0a-e053-d805fe0a78d9
|
5
|
|
The antineoplastic drug flavopiridol reverses memory impairment induced by Amyloid-ß1-42 oligomers in mice, file dfe4d227-ace2-bb0a-e053-d805fe0a78d9
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5
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Multifaceted roles of GSK-3 and Wnt/beta-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention, file dfe4d227-b564-bb0a-e053-d805fe0a78d9
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5
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|
Standardized bovine colostrum derivative impedes development of type 1 diabetes in rodents, file dfe4d22b-874c-bb0a-e053-d805fe0a78d9
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5
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|
Erratum: Inhibition of human immunodeficiency virus (HIV-1) infection in human peripheral blood leucocytes-SCID reconstituted mice by rapamycin. (Clinical and Experimental Immunology (2009) 155 (28-34)), file dfe4d22e-cc48-bb0a-e053-d805fe0a78d9
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5
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|
Meta-analysis of transcriptomic data of dorsolateral prefrontal cortex and of peripheral blood mononuclear cells identifies altered pathways in Schizophrenia, file ef967385-bc6c-43ae-a790-a6d5a71ceda4
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5
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Transcriptomic analysis reveals abnormal expression of prion disease gene pathway in brains from patients with autism spectrum disorders, file fd85c73e-e801-4761-8f64-6ede83a1ee59
|
5
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|
Exploratory analysis of iPSCS-derived neuronal cells as predictors of diagnosis and treatment of Alzheimer disease, file 109fb77b-2e8b-4c4c-8d51-a83c4d266280
|
4
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Evaluation of the Involvement of Heme Oxygenase-1 Expression in Discoid Lupus Erythematosus Lesions, file d361a78e-0ef5-4236-93a4-17fa83249062
|
4
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|
Sodium fusidate in Guillain-Barre syndrome: a case report, file dfe4d226-f6e2-bb0a-e053-d805fe0a78d9
|
4
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| Totale |
2.584 |