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A molecular Systems Medicine approach to Diabetes Mellitus pinpoints the molecular bases of the higher resistance to cytokine-induced apoptosis of mammalian pancreas α cells respect to β cells, file dfe4d227-6f60-bb0a-e053-d805fe0a78d9
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457
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1 h Postload Glycemia Is Associated with Low Endogenous Secretory Receptor for Advanced Glycation End Product Levels and Early Markers of Cardiovascular Disease, file dfe4d229-e50f-bb0a-e053-d805fe0a78d9
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56
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Trattamento dell’ipercolesterolemia nel soggetto con diabete mellito: Aggiornamento sugli approcci terapeutici, file dfe4d22c-b121-bb0a-e053-d805fe0a78d9
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40
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HbA1c identifies subjects with prediabetes and subclinical left ventricular diastolic dysfunction, file dfe4d22c-2708-bb0a-e053-d805fe0a78d9
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39
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Atorvastatin but not pravastatin impairs mitochondrial function in human pancreatic islets and rat β-cells. Direct effect of oxidative stress, file dfe4d228-9533-bb0a-e053-d805fe0a78d9
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23
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Inflammation and ventricular-vascular coupling in hypertensive patients with metabolic syndrome, file dfe4d229-8752-bb0a-e053-d805fe0a78d9
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19
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Chronic exposure to palmitate impairs insulin signaling in an intestinal L-cell line: A possible shift from GLP-1 to glucagon production, file dfe4d22d-02ca-bb0a-e053-d805fe0a78d9
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18
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Impaired Glucagon Suppression And Reduced Insulin Sensitivity In Subjects With Prediabetes Undergoing Atorvastatin Therapy, file dfe4d229-e570-bb0a-e053-d805fe0a78d9
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17
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Intestino come ghiandola endocrina, file dfe4d227-2dc6-bb0a-e053-d805fe0a78d9
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16
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Effect of PCSK9 inhibitors on pulse wave velocity and monocyte-to-HDL-cholesterol ratio in familial hypercholesterolemia subjects: results from a single-lipid-unit real-life setting, file dfe4d22e-b01e-bb0a-e053-d805fe0a78d9
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15
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Serum coding and non-coding RNAs as biomarkers of NAFLD and fibrosis severity, file 7ff3a030-be08-4574-900d-6096489e332f
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14
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Prediabete: Criteri diagnostici e rischio cardiovascolare, file dfe4d22c-ad99-bb0a-e053-d805fe0a78d9
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14
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Left ventricular geometry and periodontitis in patients with the metabolic syndrome, file dfe4d229-d81c-bb0a-e053-d805fe0a78d9
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13
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Pathophysiological, Molecular and Therapeutic Issues of Nonalcoholic Fatty Liver Disease: An Overview, file dfe4d22c-cc57-bb0a-e053-d805fe0a78d9
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13
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Low Endogenous Secretory Receptor for Advanced Glycation End-Products Levels Are Associated With Inflammation and Carotid Atherosclerosis in Prediabetes, file dfe4d227-25e4-bb0a-e053-d805fe0a78d9
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12
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Analysis of arterial stiffness and sexual function after adding on pcsk9 inhibitor treatment in male patients with familial hypercholesterolemia: A single lipid center real-world experience, file dfe4d22e-8d9e-bb0a-e053-d805fe0a78d9
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12
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Serum coding and non-coding RNAs as biomarkers of NAFLD and fibrosis severity, file dfe4d22e-aa49-bb0a-e053-d805fe0a78d9
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12
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Chronic Exposure to GLP-1 Increases GLP-1 Synthesis and Release in a Pancreatic Alpha Cell Line (α-TC1): Evidence of a Direct Effect of GLP-1 on Pancreatic Alpha Cells, file dfe4d226-fecc-bb0a-e053-d805fe0a78d9
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11
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Altered expression of uncoupling protein 2 in GLP-1-producing cells after chronic high glucose exposure: implications for the pathogenesis of diabetes mellitus., file dfe4d227-3d60-bb0a-e053-d805fe0a78d9
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11
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Analysis of HDL-microRNA panel in heterozygous familial hypercholesterolemia subjects with LDL receptor null or defective mutation, file dfe4d229-e181-bb0a-e053-d805fe0a78d9
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11
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Beta and alpha cell function in metabolically healthy but obese subjects: relationship with entero-insular axis., file dfe4d227-2f49-bb0a-e053-d805fe0a78d9
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10
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CEBPA exerts a specific and biologically important proapoptotic role in pancreatic β cells through its downstream network targets, file dfe4d227-b1b2-bb0a-e053-d805fe0a78d9
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10
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Update on pre-diabetes: Focus on diagnostic criteria and cardiovascular risk, file dfe4d227-9bfa-bb0a-e053-d805fe0a78d9
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9
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Inflammation and ventricular-vascular coupling in hypertensive patients with metabolic syndrome, file dfe4d22e-8d6f-bb0a-e053-d805fe0a78d9
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9
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Author Correction: Atorvastatin but Not Pravastatin Impairs Mitochondrial Function in Human Pancreatic Islets and Rat β-Cells. Direct Effect of Oxidative Stress, file dfe4d22e-7a00-bb0a-e053-d805fe0a78d9
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8
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miR-296-3p, miR-298-5p and their downstream networks are causally involved in the higher resistance of mammalian pancreatic α cells to cytokine-induced apoptosis as compared to β cells, file dfe4d227-702b-bb0a-e053-d805fe0a78d9
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7
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Intracellular
and extracellular miRNome deregulation in cellular models of NAFLD or NASH:
Clinical implications, file dfe4d227-1b60-bb0a-e053-d805fe0a78d9
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6
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Cardiovascular Risk Profile in Subjects With Prediabetes and New-Onset Type 2 Diabetes Identified by HbA1c According to American Diabetes Association Criteria, file dfe4d227-25c2-bb0a-e053-d805fe0a78d9
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6
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Intracellular
and extracellular miRNome deregulation in cellular models of NAFLD or NASH:
Clinical implications, file dfe4d227-b3cb-bb0a-e053-d805fe0a78d9
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5
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Analysis of steatosis biomarkers and inflammatory profile after adding on PCSK9 inhibitor treatment in familial hypercholesterolemia subjects with nonalcoholic fatty liver disease: a single lipid center real-world experience, file dfe4d22d-ec0f-bb0a-e053-d805fe0a78d9
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5
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Arterial stiffness improvement after adding on PCSK9 inhibitors or ezetimibe to high-intensity statins in patients with familial hypercholesterolemia: A Two-Lipid Center Real-World Experience, file dfe4d22a-5914-bb0a-e053-d805fe0a78d9
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4
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May statins and PCSK9 inhibitors be protective from COVID-19 in familial hypercholesterolemia subjects?, file dfe4d22c-4001-bb0a-e053-d805fe0a78d9
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4
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Analysis of S100A12 plasma levels in hyperlipidemic subjects with or without familial hypercholesterolemia, file dfe4d22c-e0ca-bb0a-e053-d805fe0a78d9
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4
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Low circulating vitamin D levels are associated with increased arterial stiffness in prediabetic subjects identified according to HbA1c, file dfe4d227-1911-bb0a-e053-d805fe0a78d9
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3
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Palmitate affects insulin receptor phosphorylation and intracellular insulin signal in a pancreatic alpha-cell line, file dfe4d227-890e-bb0a-e053-d805fe0a78d9
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3
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Effects of Metformin on oxidative stress, adenine nucleotides balance and glucose-induced insulin release impaired by chronic FFA exposure in rat pancreatic islets, file dfe4d227-a80e-bb0a-e053-d805fe0a78d9
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3
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HbA1c increase is associated with higher coronary and peripheral atherosclerotic burden in non diabetic patients, file dfe4d227-aba9-bb0a-e053-d805fe0a78d9
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3
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Glucosamine-induced alterations of mitochondrial function in pancreatic beta-cells: possible role of protein glycosylation., file dfe4d227-adab-bb0a-e053-d805fe0a78d9
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3
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High intake of dietary advanced glycation end-products is associated with increased arterial stiffness and inflammation in subjects with type 2 diabetes, file dfe4d22c-ff99-bb0a-e053-d805fe0a78d9
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3
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Detecting familial hypercholesterolemia by serum lipid profile screening in a hospital setting: Clinical, genetic and atherosclerotic burden profile, file dfe4d22e-9511-bb0a-e053-d805fe0a78d9
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3
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Functional and morphological alterations of mitochondria in pancreatic beta cells from type 2 diabetic patients, file dfe4d227-1096-bb0a-e053-d805fe0a78d9
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2
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Therapeutic options for elderly diabetic subjects: open label, randomized clinical trial of insulin glargine added to oral antidiabetic drugs versus increased dosage of oral antidiabetic drugs, file dfe4d227-121c-bb0a-e053-d805fe0a78d9
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2
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Alpha- and beta-cell abnormalities in haemoglobin A1c-defined prediabetes and type 2 diabetes, file dfe4d227-25c1-bb0a-e053-d805fe0a78d9
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2
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Incretin-based therapies: a focus on alpha cells and glucagon secretion., file dfe4d227-2d00-bb0a-e053-d805fe0a78d9
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2
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Metformin restores insulin secretion altered by chronic exposure to free fatty acids or high glucose: a direct metformin effect on pancreatic beta cells, file dfe4d227-4178-bb0a-e053-d805fe0a78d9
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2
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Elevated Plasma Glucose-dependent Insulinotropic Polypeptide Associates with Hyperinsulinemia in Metabolic Syndrome, file dfe4d227-9dc5-bb0a-e053-d805fe0a78d9
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2
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New treatment options for lipid-lowering therapy in subjects with type 2 diabetes, file dfe4d22c-b58a-bb0a-e053-d805fe0a78d9
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2
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High glomerular filtration rate is associated with impaired arterial stiffness and subendocardial viability ratio in prediabetic subjects, file dfe4d22e-adb2-bb0a-e053-d805fe0a78d9
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2
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Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress, file 071175eb-e5ef-4944-b901-97ed3e707d1e
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1
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Diabetes increases renovascular impedance in patients with liver cirrhosis, file 9fb6c88d-a94f-4525-bb32-6894263cca75
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1
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Effects of n-3 polyunsaturated fatty acids in subjects with nonalcoholic fatty liver disease, file dfe4d226-fc54-bb0a-e053-d805fe0a78d9
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1
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Low advanced glycation end product diet improves the lipid and inflammatory profiles of prediabetic subjects, file dfe4d227-1536-bb0a-e053-d805fe0a78d9
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1
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Hexokinase shift to mitochondria is associated with an increased sensitivity to glucose in rat pancreatic islets, file dfe4d227-174e-bb0a-e053-d805fe0a78d9
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1
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Hepatic insulin resistance in NAFLD: relationship with markers of atherosclerosis and metabolic syndrome components, file dfe4d227-1908-bb0a-e053-d805fe0a78d9
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1
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Glucotoxicity and lipotoxicity in the beta cell, file dfe4d227-20ee-bb0a-e053-d805fe0a78d9
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1
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Assessment of adrenocortical reserve in stable patients with cirrhosis, file dfe4d227-276f-bb0a-e053-d805fe0a78d9
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1
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Early phase insulin secretion is increased in subjects with normal fasting glucose and metabolic syndrome: a premature feature of beta-cell dysfunction, file dfe4d227-9205-bb0a-e053-d805fe0a78d9
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1
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Direct apoptotic effects of free fatty acids on human endothelial cells, file dfe4d227-9ec7-bb0a-e053-d805fe0a78d9
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1
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An increased waist-to-hip ratio is a key determinant of atherosclerotic burden in overweight subjects, file dfe4d228-fd1c-bb0a-e053-d805fe0a78d9
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1
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Separate impact of metabolic syndrome and altered glucose tolerance on early markers of vascular injuries., file dfe4d22b-5329-bb0a-e053-d805fe0a78d9
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1
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High TG to HDL ratio plays a significant role on atherosclerosis extension in prediabetes and newly diagnosed type 2 diabetes subjects, file dfe4d22c-6ddb-bb0a-e053-d805fe0a78d9
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1
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Totale |
960 |