Sperm DNA and membrane are highly susceptible to reactive oxygen species (ROS), which are able to cause DNA fragmentation and membrane lipoperoxidation • Treatment with antioxidants represents a valid therapeutic option for male infertility, especially after the sperm ROS-induced damage has been ascertained • Several compounds with antioxidant properties have been developed • Founded on an evidence-based medicine criterion, vitamin C and E, carnitines and coezyme Q10 may be proposed as first-line treatment, while gluthatione, zinc, lycopene and myoinositol as second-line
Antioxidants in the medical and surgical management of male infertility
Cannarella R;Lanzafame F;Condorelli R A;Calogero AE;La Vignera S
2020-01-01
Abstract
Sperm DNA and membrane are highly susceptible to reactive oxygen species (ROS), which are able to cause DNA fragmentation and membrane lipoperoxidation • Treatment with antioxidants represents a valid therapeutic option for male infertility, especially after the sperm ROS-induced damage has been ascertained • Several compounds with antioxidant properties have been developed • Founded on an evidence-based medicine criterion, vitamin C and E, carnitines and coezyme Q10 may be proposed as first-line treatment, while gluthatione, zinc, lycopene and myoinositol as second-lineFile in questo prodotto:
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