Background and aims: To date, there are inconclusive evidences for a protective effect of coffee consumption on the occurrence and course of age-related neurological and neuropsychiatric disorders. Moreover, no study has been carried out in mild vascular cognitive impairment and latelife depression. Methods: We assessed the association between different quantities of mocha coffee consumption over the last year on both cognitive and mood performance in a non-demented elderly Italian population with subcortical ischemic vascular disease (SIVD). The outcome measures were Mini Mental State Examination (MMSE), Stroop Color-Word Interference test (Stroop T), 17-items Hamilton Depression Rating Scale (HDRS), Activities of Daily Living (ADL), and Instrumental ADL scores. Results: MMSE, HDRS, and Stroop T independently and significantly correlated with coffee consumption, i.e., better scores with increasing intake. Post-hoc analyses showed that the group with a moderate coffee intake (2 cups/day) had similar values compared to the heavily drinkers (3 cups/ day), with the exception of MMSE score. Conclusion: Daily coffee consumption was associated with better cognitive performance and mood status, with a significant dose-response effect even with a moderate intake. These findings might have translational implications for the identification of modifiable factors for the occurrence and severity of vascular dementia and geriatric depression.

Mocha coffee consumption correlates with cognitive function in a population with subcortical ischemic vascular disease

Francesco Fisicaro
Primo
;
Giuseppe Lanza
Secondo
;
Manuela Pennisi;Carla Vagli;Mariagiovanna Cantone;Giovanni Pennisi
Penultimo
;
Rita Bella
Ultimo
2021

Abstract

Background and aims: To date, there are inconclusive evidences for a protective effect of coffee consumption on the occurrence and course of age-related neurological and neuropsychiatric disorders. Moreover, no study has been carried out in mild vascular cognitive impairment and latelife depression. Methods: We assessed the association between different quantities of mocha coffee consumption over the last year on both cognitive and mood performance in a non-demented elderly Italian population with subcortical ischemic vascular disease (SIVD). The outcome measures were Mini Mental State Examination (MMSE), Stroop Color-Word Interference test (Stroop T), 17-items Hamilton Depression Rating Scale (HDRS), Activities of Daily Living (ADL), and Instrumental ADL scores. Results: MMSE, HDRS, and Stroop T independently and significantly correlated with coffee consumption, i.e., better scores with increasing intake. Post-hoc analyses showed that the group with a moderate coffee intake (2 cups/day) had similar values compared to the heavily drinkers (3 cups/ day), with the exception of MMSE score. Conclusion: Daily coffee consumption was associated with better cognitive performance and mood status, with a significant dose-response effect even with a moderate intake. These findings might have translational implications for the identification of modifiable factors for the occurrence and severity of vascular dementia and geriatric depression.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/20.500.11769/510535
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