Autoimmune inner ear disease (AIED) encompassed a diverse group of disorders in which immune-mediated damage to vestibulocochlear apparatus results in hearing loss, tinnitus, or vestibular impairment. The underlying pathogenesis involves inflammatory response with self-reactive antibodies and T-cells injuring structures. These insults induce electrochemical disturbances, microthrombosis, and immune cell deposition within the structures of the inner ear. AIED may be a primary disorder or accompany systemic disease. In this chapter, we discuss the etiology of the hearing loss, tinnitus and vestibular disorders in patients affected by autoimmune disorders
ETIOLOGY AND PATHOGENESIS OF AUDITORY AND VESTIBULAR DYSFUNCTION IN PATIENTS WITH AUTOIMMUNE DISORDERS
Di Stadio A;
In corso di stampa
Abstract
Autoimmune inner ear disease (AIED) encompassed a diverse group of disorders in which immune-mediated damage to vestibulocochlear apparatus results in hearing loss, tinnitus, or vestibular impairment. The underlying pathogenesis involves inflammatory response with self-reactive antibodies and T-cells injuring structures. These insults induce electrochemical disturbances, microthrombosis, and immune cell deposition within the structures of the inner ear. AIED may be a primary disorder or accompany systemic disease. In this chapter, we discuss the etiology of the hearing loss, tinnitus and vestibular disorders in patients affected by autoimmune disordersI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
