Surface plasmon resonance represents a new tool for the simple, fast and cheap nucleic acid detection. Large efforts have been paid during the last decade with the aim to develop even more sensitive and specific SPR-based methods to be used for the direct detection of genomic DNA. This Chapter, after a description of fundamentals of surface plasmon resonance and allied techniques, will review the state-of-the-art of recent platform and assay developments and will provide an overview of recent uses of SPR techniques for the direct detection of non-amplified nucleic acids.
Surface plasmon resonance-based methods
D'AGATA, ROBERTA;SPOTO, Giuseppe
2012-01-01
Abstract
Surface plasmon resonance represents a new tool for the simple, fast and cheap nucleic acid detection. Large efforts have been paid during the last decade with the aim to develop even more sensitive and specific SPR-based methods to be used for the direct detection of genomic DNA. This Chapter, after a description of fundamentals of surface plasmon resonance and allied techniques, will review the state-of-the-art of recent platform and assay developments and will provide an overview of recent uses of SPR techniques for the direct detection of non-amplified nucleic acids.File in questo prodotto:
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