The delayed luminescence spectroscopy as tool to investigate the cytotoxic effect on human cancer cells of drug-loaded nanostructured lipid carrier.

The first results concerning the possibility to use Delayed Luminescencespectroscopy to evaluate the in vitro induction of cytotoxic effects onhuman glioblastoma cells of nanostructured lipid carrier and drug-loadednanostructured lipid carrier are showed in this contribution. We testedthe effects of nanostructured lipid carrier, ferulic acid and ferulicacidloaded nanostructured lipid carrier on U-87MG cell line. The studyseems to confirm the ability of Delayed Luminescence to be sensibleindicator of alterations induced on functionality of the mitochondrialrespiratory chain complex I in U-87MG cancer cells when treated withnanostructured lipid carriers.