We present here a new class of cleft-like receptor molecules containing two or four phosphonates anions, tailored for multipoint binding of their substrates. Depending on the accessibility of the cleft, these hosts are water soluble and selective for short or long alpha, omega-diammonium compounds. Due to their inherent chirality, we found that only those host-guest combinations which allow a three-point-interaction were effective.

We present here a new class of cleft-like receptor molecules containing two or four phosphonates anions, tailored for multipoint binding of their substrates. Depending on the accessibility of the cleft, these hosts are water soluble and selective for short or long alpha, omega-diammonium compounds. Due to their inherent chirality, we found that only those host-guest combinations which allow a three-point-interaction were effective.

Conformationally rigid hosts containing phosphonic units

FAILLA, Salvatore;CONSIGLIO, GIUSEPPE;
2002-01-01

Abstract

We present here a new class of cleft-like receptor molecules containing two or four phosphonates anions, tailored for multipoint binding of their substrates. Depending on the accessibility of the cleft, these hosts are water soluble and selective for short or long alpha, omega-diammonium compounds. Due to their inherent chirality, we found that only those host-guest combinations which allow a three-point-interaction were effective.
2002
We present here a new class of cleft-like receptor molecules containing two or four phosphonates anions, tailored for multipoint binding of their substrates. Depending on the accessibility of the cleft, these hosts are water soluble and selective for short or long alpha, omega-diammonium compounds. Due to their inherent chirality, we found that only those host-guest combinations which allow a three-point-interaction were effective.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11769/10352
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