[GRAPHICS] We provide access to a new class of C-1- or C-2-symmetrical host molecules 1 and 2 based on a spirobisindane skeleton, Whereas 1 is selective for short, rigid diamines, 2 prefers longer alpha,omega-dications. Of all the amino acid methyl esters, only those of lysine and arginine with the correct distance between their cationic groups form strong 1:1 complexes in DMSO with 2, NMR titrations reveal high association constants as well as discrimination between the enantiomers of lysine and arginine.
[GRAPHICS] We provide access to a new class of C-1- or C-2-symmetrical host molecules 1 and 2 based on a spirobisindane skeleton, Whereas 1 is selective for short, rigid diamines, 2 prefers longer alpha,omega-dications. Of all the amino acid methyl esters, only those of lysine and arginine with the correct distance between their cationic groups form strong 1:1 complexes in DMSO with 2, NMR titrations reveal high association constants as well as discrimination between the enantiomers of lysine and arginine.
A chiral sensor for arginine and lysine
FAILLA, Salvatore;CONSIGLIO, GIUSEPPE
2000-01-01
Abstract
[GRAPHICS] We provide access to a new class of C-1- or C-2-symmetrical host molecules 1 and 2 based on a spirobisindane skeleton, Whereas 1 is selective for short, rigid diamines, 2 prefers longer alpha,omega-dications. Of all the amino acid methyl esters, only those of lysine and arginine with the correct distance between their cationic groups form strong 1:1 complexes in DMSO with 2, NMR titrations reveal high association constants as well as discrimination between the enantiomers of lysine and arginine.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
