Some carboxymethyl- and carboxy-derivatives of 7H- and 5H-1,2,4-triazolo [3,4-b][1,3,4] thiadiazine were prepared. Their structure are discussed on the basis of IR, NMR and mass spectra. The synthesized compounds were subjected to a preliminary pharmacological screening for antiinflammatory-analgesic activity and to microbiological test on various species of mycetes and bacteria.
CARBOXYMETHYL-DERIVATIVE AND CARBOXY-DERIVATIVE OF 7H-1,2,4-TRIAZOLO AND 5H-1,2,4-TRIAZOLO [3,4-B][1,3,4] THIADIAZINE - SYNTHESIS AND BIOLOGICAL EVALUATION
BONINA, Francesco Paolo;PIGNATELLO, Rosario;PANICO, Anna Maria;BLANDINO, Giovanna
1989-01-01
Abstract
Some carboxymethyl- and carboxy-derivatives of 7H- and 5H-1,2,4-triazolo [3,4-b][1,3,4] thiadiazine were prepared. Their structure are discussed on the basis of IR, NMR and mass spectra. The synthesized compounds were subjected to a preliminary pharmacological screening for antiinflammatory-analgesic activity and to microbiological test on various species of mycetes and bacteria.File in questo prodotto:
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