Metyrapone [2-methyl-1,2-di(3-pyridyl)propan-2-one, 1] undergoes efficient a-cleavage via the n(o) pi* triplet. The fate of the resulting acyl and alkyl radicals has been determined by transient studies as well as through the isolation of the final products, quantum yield measurements and trapping studies. Processes previously documented for carbocyclic analogues of 1, such as disproportionation and coupling of the alkyl radicals nd recombination to the starting compound are here accompanied by another major process, viz. coupling with attack of the acyl radical on the pyridine ring, which eventually leads mainly to a polymeric material. RI Monti, Sandra/B-9272-2009; Sortino, Salvatore/E-4684-2011
The photochemistry of metyrapone
SORTINO, Salvatore;
1996-01-01
Abstract
Metyrapone [2-methyl-1,2-di(3-pyridyl)propan-2-one, 1] undergoes efficient a-cleavage via the n(o) pi* triplet. The fate of the resulting acyl and alkyl radicals has been determined by transient studies as well as through the isolation of the final products, quantum yield measurements and trapping studies. Processes previously documented for carbocyclic analogues of 1, such as disproportionation and coupling of the alkyl radicals nd recombination to the starting compound are here accompanied by another major process, viz. coupling with attack of the acyl radical on the pyridine ring, which eventually leads mainly to a polymeric material. RI Monti, Sandra/B-9272-2009; Sortino, Salvatore/E-4684-2011I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
