A new naphthalimide derivative bearing a tetrathia-azacrown for high affinity and selective binding to Cu+ was synthesised. Copper recognition properties in solution were evaluated using 1H NMR and fluorescence spectroscopy. Live cell imaging by confocal microscopy highlighted the capabilities of the newsensor for the two-wavelength detection of intracellular monovalent copper in neuronal cells.

A ratiometric naphthalimide sensor for live cell imaging of copper(I)

SATRIANO, Cristina;TRUSSO SFRAZZETTO, GIUSEPPE;AMATO, Maria Emanuela;BALLISTRERI, Francesco Paolo;COPANI, Agata Graziella;GRASSO, GIUSEPPE;PAPPALARDO, ANDREA;TOMASELLI, Gaetano;TOSCANO, Rosa Maria
2013

Abstract

A new naphthalimide derivative bearing a tetrathia-azacrown for high affinity and selective binding to Cu+ was synthesised. Copper recognition properties in solution were evaluated using 1H NMR and fluorescence spectroscopy. Live cell imaging by confocal microscopy highlighted the capabilities of the newsensor for the two-wavelength detection of intracellular monovalent copper in neuronal cells.
SELECTIVE FLUORESCENT SENSOR; LIVING CELLS, MICROSCOPY; DYES
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11769/14037
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 41
  • ???jsp.display-item.citation.isi??? 41
social impact