We report correlations between ANP and systolic function indexes, and between ANP and left ventricular diastolic volumes/ m2, all assessed by echocardiography. However, the lack of correlation between atnal dimension and ANP in the study of Korup et al is not totally convincing, and its is shown a fair positive correlation; we find weak correlations between LAD/m2 and ANP. In addition, a significant correlation between ANP and diastolic measurements, notably E/A ratio, is observed in congestive heart failure and the clinical improvement is associated both with a decrease in the abnormality of diastolic echocardiographic measurements and with the decrease of ANP121. A correlation between ANP and heart rate, which we reported in sinus rhythm patients, both in the control groups and in congestive heart failure, but not in patients with chronic atrial fibrillation was not observed elsewhere. If patients with arrhythmias had been included, the correlation between heart rate and ANP may have been lacking in groups of patients considered globally. Finally, an additional point should be taken into account, that of the close positive relationship present in many studies, between age and ANP. This can affect the final results in many ways, particularly in groups with a wide age range.
|Titolo:||Plasma ANP and systolic function in myocardial infarction|
|Data di pubblicazione:||1996|
|Appare nelle tipologie:||1.1 Articolo in rivista|