Glucobrassicin (GBS), a glucosinolate contained in many brassica vegetables, is the precursor of chemopreventivecompounds such as indole-3-carbinol. Large amounts of GBS would be needed to perform studies aimed at elucidating itsrole in the diet. This studywasmainly undertaken to evaluate the flower buds of Isatis canescens as a source forGBS purification.In order to investigate the health-promoting potential of this species, glucosinolate, phenol and flavonoid content aswell as thewhole antioxidant capacity were also determined. Flower bud samples were collected in four localities around Mount Etna inSicily, Italy, where I. canescens is widespread, as they are locally traditionally eaten.RESULTS: I. canescens flower buds displayed high GBS concentrations, up to 60 mol g−1 dry weight. The purification methodconsisted of two chromatographic steps,which made it possible to obtain GBSwith a purity of 92–95%,with a yield of 21 g kg−1.The total glucosinolates, phenols, flavonoids and antioxidant activitywere considerable,with the southern locality showing thehighest concentrations for all the phytochemicals.CONCLUSION: I. canescens flower buds represent a naturally rich source of GBS, at a level suitable for its purification.Furthermore, flower bud consumption could provide an intake of health-promoting compounds, with possible antioxidant andchemopreventive properties.

Isatis canescens is a rich source of glucobrassicin and other health-promoting compounds

BRANCA, Ferdinando;
2014

Abstract

Glucobrassicin (GBS), a glucosinolate contained in many brassica vegetables, is the precursor of chemopreventivecompounds such as indole-3-carbinol. Large amounts of GBS would be needed to perform studies aimed at elucidating itsrole in the diet. This studywasmainly undertaken to evaluate the flower buds of Isatis canescens as a source forGBS purification.In order to investigate the health-promoting potential of this species, glucosinolate, phenol and flavonoid content aswell as thewhole antioxidant capacity were also determined. Flower bud samples were collected in four localities around Mount Etna inSicily, Italy, where I. canescens is widespread, as they are locally traditionally eaten.RESULTS: I. canescens flower buds displayed high GBS concentrations, up to 60 mol g−1 dry weight. The purification methodconsisted of two chromatographic steps,which made it possible to obtain GBSwith a purity of 92–95%,with a yield of 21 g kg−1.The total glucosinolates, phenols, flavonoids and antioxidant activitywere considerable,with the southern locality showing thehighest concentrations for all the phytochemicals.CONCLUSION: I. canescens flower buds represent a naturally rich source of GBS, at a level suitable for its purification.Furthermore, flower bud consumption could provide an intake of health-promoting compounds, with possible antioxidant andchemopreventive properties.
glucosinolate; ORAC; chemoprevention
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11769/15556
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