Rhabdomyomatous mesenchymal hamartoma (RMH) is a rare tumour-like lesion which occurs in the skin of newborns, principally of the face and neck. RMH has also been reported in unusual sites, including oral cavity, nasal vestibule and vagina. In this case report we describe a rare case of RMH arising as a nodular mass at the anal margin of a male newborn. This is an unusual site for such a rare lesion. The histological examination of the lesion showed the typical features of RMH. Desmin and S100 expression has been determined by immunohistochemical analyses to assess the distribution of the mature skeletal muscle cells and small-sized nerves, which represented the principal components of the nodular mass. In conclusion our case emphasizes the possibility that RMH may occur in the perianal region and awareness of this possibility is crucial for pathologists to avoid confusion with other skeletal muscle-containing lesions, especially rhabdomyosarcoma

Rhabdomyomatous mesenchymal hamartoma (RMH) of the anal region: an unusual location for such a rare lesion

MUSUMECI, GIUSEPPE
Secondo
;
MAGRO, Gaetano Giuseppe
Ultimo
2014

Abstract

Rhabdomyomatous mesenchymal hamartoma (RMH) is a rare tumour-like lesion which occurs in the skin of newborns, principally of the face and neck. RMH has also been reported in unusual sites, including oral cavity, nasal vestibule and vagina. In this case report we describe a rare case of RMH arising as a nodular mass at the anal margin of a male newborn. This is an unusual site for such a rare lesion. The histological examination of the lesion showed the typical features of RMH. Desmin and S100 expression has been determined by immunohistochemical analyses to assess the distribution of the mature skeletal muscle cells and small-sized nerves, which represented the principal components of the nodular mass. In conclusion our case emphasizes the possibility that RMH may occur in the perianal region and awareness of this possibility is crucial for pathologists to avoid confusion with other skeletal muscle-containing lesions, especially rhabdomyosarcoma
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/20.500.11769/16886
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact