The population structure of two alleles with similar characteristics, HbS and beta-thalassemia, was studied in the same area in Sicily. It was observed that beta-thalassemia has uniform frequencies over the island, and that HbS shows a South-North cline. A singularity exists for HbS in the town of Butera, where the frequency of the S gene is six times higher than the island average. It was suggested that HbS entered Sicily from Greece (or directly from North Africa) when the beta-thalassemia allele was already established in the Island
Titolo: | Population structure of Sicily: b-thalassemia and Hb S. Hum Genet 75:1, 1987 |
Autori interni: | |
Data di pubblicazione: | 1987 |
Rivista: | |
Handle: | http://hdl.handle.net/20.500.11769/1765 |
Appare nelle tipologie: | 1.1 Articolo in rivista |
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