(Graph Presented) A combination of atomic force microscopy, quartz crystal microbalance and fluorescence spectroscopy shed light on the mechanism of interaction of hIAPP with zwitterionic model membranes, and allowed us to speculate the toxic behaviour of hIAPP in diabetes mellitus type II. The results suggest that damage of zwitterionic lipid bilayers and fibrillogenesis are two different phenomena.
Self-Assembling Pathway of HiApp Fibrils within Lipid Bilayers
Scalisi SPrimo
;MARLETTA, GiovanniPenultimo
;LA ROSA, Carmelo
Ultimo
2010-01-01
Abstract
(Graph Presented) A combination of atomic force microscopy, quartz crystal microbalance and fluorescence spectroscopy shed light on the mechanism of interaction of hIAPP with zwitterionic model membranes, and allowed us to speculate the toxic behaviour of hIAPP in diabetes mellitus type II. The results suggest that damage of zwitterionic lipid bilayers and fibrillogenesis are two different phenomena.File in questo prodotto:
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