Gastric cancer: prognostic significance of the Goseki histological classification

Gastric cancer: prognostic significance of the Goseki histological classification. B. Sciiletta,R. Lanteri, C. Rapisarda, L Greco, S. Lanzafame, A. Torrisi, S. Puleo, A. Licata.The aim of this study was to evaluate the prognostic significance of the Goseki factor inpatients undergoing potentially curative resection for gastric cancer. From 1989 to 1999202 patients with gastric cancer carne in for observation to the 1st Surgical Clinic of CataniaUniversity. For the purposes of this study we examined 86 patients with a 5-year follow-up, from whom it was possible to obtain samples which were mounted in paraffinblocks and stained (haematoxylin-eosin and PAS-Aician blue). The 5-year survival ratesof patients with Goseki l and Il tumours with good tubular differentiation were 90% and30o/o as compared with 42°/o and 32% in patients with tumours that showed poor tubulardifferentiation (Goseki III and IV). In contrast the 5-year survival rates in patients withmucin-poor tumours (Goseki l and 111) were 90% and 42o/o, as against 30% and 32% in patients with mucin-rich tumours (P