The in vitro activity of flurithromycin, a 14-membered macrolide drug, was found to be similar to thatof erythromycin against 41 strains of Mycoplasma spp. and 100 strains of Ureaplasma urealyticum. All 28 strains of Mycoplasma hominis were uniformly resistant to both macrolides with MICs > 256mg/L, U. urealyticum showed intermediate resistance with MIC50, s of 0.5 and 1 mg/Lfor erythromycin and flurithromycin, respectively, whereas the ten strains of Mycoplasma pneumonia were susceptible to ≤ 0.03 mg/L of both macrolides.
In-vitro antimycoplasmal activity of flurithromycin
FURNERI, Pio Maria;TEMPERA, Gianna;
1995-01-01
Abstract
The in vitro activity of flurithromycin, a 14-membered macrolide drug, was found to be similar to thatof erythromycin against 41 strains of Mycoplasma spp. and 100 strains of Ureaplasma urealyticum. All 28 strains of Mycoplasma hominis were uniformly resistant to both macrolides with MICs > 256mg/L, U. urealyticum showed intermediate resistance with MIC50, s of 0.5 and 1 mg/Lfor erythromycin and flurithromycin, respectively, whereas the ten strains of Mycoplasma pneumonia were susceptible to ≤ 0.03 mg/L of both macrolides.File in questo prodotto:
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