Available evidence on the practice of acute pharmacological challenge tests in parkinsonian patients was reviewed by a committee of experts, which achieved a general consensus. The published data deal mainly with the acute administration of levodopa and apomorphine in Parkinson's disease. Such challenge may serve different purposes, e.g., research. diagnosis, or tailoring of treatment. Unique protocols describing the clinical setting and practice parameters are not available. The present paper describes the scientific background and supplies practical guidelines, whenever possible, to perform and evaluate acute challenge tests in parkinsonian syndromes. With the appropriate indication and setting. acute challenge tests are useful in diagnosis and therapy of Parkinson's disease and related disorders

Consensus statement on the role of acute dopaminergic challenge in Parkinson's disease

ZAPPIA, MARIO
2001-01-01

Abstract

Available evidence on the practice of acute pharmacological challenge tests in parkinsonian patients was reviewed by a committee of experts, which achieved a general consensus. The published data deal mainly with the acute administration of levodopa and apomorphine in Parkinson's disease. Such challenge may serve different purposes, e.g., research. diagnosis, or tailoring of treatment. Unique protocols describing the clinical setting and practice parameters are not available. The present paper describes the scientific background and supplies practical guidelines, whenever possible, to perform and evaluate acute challenge tests in parkinsonian syndromes. With the appropriate indication and setting. acute challenge tests are useful in diagnosis and therapy of Parkinson's disease and related disorders
File in questo prodotto:
File Dimensione Formato  
Consensus statement on the role of acute dopaminergic challenge in Parkinson's disease.pdf

solo gestori archivio

Tipologia: Versione Editoriale (PDF)
Dimensione 33.6 kB
Formato Adobe PDF
33.6 kB Adobe PDF   Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11769/22967
Citazioni
  • ???jsp.display-item.citation.pmc??? 22
  • Scopus 109
  • ???jsp.display-item.citation.isi??? 104
social impact