Metal dyshomeostasis is involved in several pathologies, making metal ions promising therapeutic targets. Conjugating 8-hydroxyquinolines with sugars gave rise to novel derivatives with improved solubility, selectivity, and multifunctionality. Biological evaluation of these compounds suggests they have potential as therapeutic agents in diseases related to metal dyshomeostasis.
New Glycoconjugates for the Treatment of Diseases Related to Metal Dyshomeostasis
OLIVERI, VALENTINA
Ultimo
2015
Abstract
Metal dyshomeostasis is involved in several pathologies, making metal ions promising therapeutic targets. Conjugating 8-hydroxyquinolines with sugars gave rise to novel derivatives with improved solubility, selectivity, and multifunctionality. Biological evaluation of these compounds suggests they have potential as therapeutic agents in diseases related to metal dyshomeostasis.File in questo prodotto:
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New Glycoconjugates for the Treatment of Diseases Related to Metal Dyshomeostasis.pdf
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