Medulloblastoma is a rare tumor in central nervous system, with an even rarer occurrence in adulthood. The management ofa recurrent disease is a medical challenge; chemotherapy has been used as the treatment of choice, while reirradiation has beenemployed in selected cases. We report the case of a 51-year-old man with recurrent medulloblastoma. He was treated with localreirradiation, chemotherapy, and antiangiogenic drug, with the latter giving the longer progression-free interval. The aim ofthis report is to show that recurrent medulloblastoma in adults can be approached with a multimodality treatment and thatantiangiogenic therapy should have a role in the management of this disease.

ANTIANGIOGENIC THERAPY IN THE TREATMENT OF RECURRENT MEDULLOBLASTOMA IN THE ADULT: CASE REPORT AND REVIEW OF THE LITERATURE

PRIVITERA, Giuseppe;SPATOLA, CORRADO
2009

Abstract

Medulloblastoma is a rare tumor in central nervous system, with an even rarer occurrence in adulthood. The management ofa recurrent disease is a medical challenge; chemotherapy has been used as the treatment of choice, while reirradiation has beenemployed in selected cases. We report the case of a 51-year-old man with recurrent medulloblastoma. He was treated with localreirradiation, chemotherapy, and antiangiogenic drug, with the latter giving the longer progression-free interval. The aim ofthis report is to show that recurrent medulloblastoma in adults can be approached with a multimodality treatment and thatantiangiogenic therapy should have a role in the management of this disease.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/20.500.11769/25967
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