Treatment of isoxazolidine derivatives with methyl iodide, followed by simple heating with aqueous NaOH, gives rise to a competitive formation of alpha,beta-enones and tetahydro-1,3-oxazines. The ring-opening process is controlled by the stereochemistry of H-5 which represents the driving factor of two competitive reaction routes.
Ring-opening of isoxazolidine nucleus: Competitive formation of α,β-enones and tetrahydro-1,3-oxazines
CHIACCHIO, Ugo;RESCIFINA, Antonio;
1995-01-01
Abstract
Treatment of isoxazolidine derivatives with methyl iodide, followed by simple heating with aqueous NaOH, gives rise to a competitive formation of alpha,beta-enones and tetahydro-1,3-oxazines. The ring-opening process is controlled by the stereochemistry of H-5 which represents the driving factor of two competitive reaction routes.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
