Background Both motor and non-motor symptoms could contribute to significant deterioration of psychological well-being in patients with Parkinsonâs disease (PD). However, its assessment has been only indirectly evaluated using tools based on health-related quality of life (HRQoL), such as the PDQ-39 scale. Objectives To evaluate psychological well-being in PD using a specific tool of assessment, the Psychological Well-being Scale (PWS), and its clinical correlates. Methods This article reports data of patientsâ perception of health state, as measured by means of the PWS, from an epidemiological, cross-sectional study conducted in Italian PD patients (FORTE Study). We tested possible relationship between well-being and clinical characteristics including fatigue, depression, sleep disruption and HRQoL. Results 272 patients completed the PWS questionnaire. Significant and clinically-relevant correlations were found between PWS total score and Parkinsonâs Fatigue Scale, Beck Depression Inventory, UPDRS Section I, PD Sleep Scale and PDQ-39 for HRQoL scores. Only clinically negligible correlations were found between PWS and motor scores. Conclusions Non-motor symptoms have a significant impact on psychological well-being in PD patients.
Titolo: | Factors influencing psychological well-being in patients with Parkinson’s disease |
Autori interni: | ZAPPIA, MARIO (Corresponding) |
Data di pubblicazione: | 2017 |
Rivista: | |
Handle: | http://hdl.handle.net/20.500.11769/317469 |
Appare nelle tipologie: | 1.1 Articolo in rivista |
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Plos One 2017.pdf | Versione Editoriale (PDF) | Open Access Visualizza/Apri |