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EnglishAmino-terminated mesoporous silica nanoparticles embedding carbon dots (MSCD) formed by calcination were functionalized with a nitric oxide (NO) photodonor (1) to give a robust MSCD-1 conjugate. The intense fluorescence of MSCDs was strongly quenched in MSCD-1 by effective energy transfer. Visible light excitation of MSCD-1 liberates NO, suppresses the energy transfer mechanism and leads to concomitant fluorescence restoration of the MSCD scaffold, which acts as an optical reporter for the released NO. The MSCD-1 hybrid is also able to encapsulate the highly hydrophobic photosensitizer temoporfin, preserving the fluorescence reporting function
| Titolo: | Multivalent mesoporous silica nanoparticles photo-delivering nitric oxide with carbon dots as fluorescence reporters | |
| Autori interni: | SORTINO, Salvatore (Corresponding) | |
| Data di pubblicazione: | 2017 | |
| Rivista: | ||
| Handle: | http://hdl.handle.net/20.500.11769/318599 | |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
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