An innovative chemical strategy integrated in a miniaturized electrochemical device was developed for sensitive detection of a pathogen genome (HBV virus) without any amplification step. The results show a limit of detection comparable to the standard qRT-PCR method (20 copies per reaction), paving the way to future development of genetic PoC devices addressing automatized and low-cost molecular diagnostics.
|Titolo:||An innovative chemical strategy for PCR-free genetic detection of pathogens by an integrated electrochemical biosensor|
|Data di pubblicazione:||2017|
|Appare nelle tipologie:||1.1 Articolo in rivista|