An innovative chemical strategy integrated in a miniaturized electrochemical device was developed for sensitive detection of a pathogen genome (HBV virus) without any amplification step. The results show a limit of detection comparable to the standard qRT-PCR method (20 copies per reaction), paving the way to future development of genetic PoC devices addressing automatized and low-cost molecular diagnostics.
Titolo: | An innovative chemical strategy for PCR-free genetic detection of pathogens by an integrated electrochemical biosensor |
Autori interni: | |
Data di pubblicazione: | 2017 |
Rivista: | |
Handle: | http://hdl.handle.net/20.500.11769/320976 |
Appare nelle tipologie: | 1.1 Articolo in rivista |
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