Introduction: Porocarcinoma is a rare sort of skin cancer developing from eccrine sweat glands, with a very rare location to the eyelid. Surgery is the unique form of treatment reported in the literature. We use radiotherapy for a case of an almost centenary man who suffered from an histologically proven porocarcinoma at the level of the left inferior eyelid. Materials and methods: We made a treatment plan comparison between photon-beam and proton-beam radiotherapy and chose the latter due to the favourable dose distribution of charged particles. Irradiation was delivered through an extreme hypofractionation Results: A rapid complete response was obtained. No relevant effects have been reported and visual function is maintained. Conclusions: This is the first case of use of proton-beam radiotherapy for the treatment of eyelid porocarcinoma. We believe that protontherapy can become a valid alternative to surgery for this type of cancer.

Porocarcinoma of the eyelid treated with proton beam radiotherapy: Case report and literature review

Giuseppe Privitera;Luigi Raffaele;Vincenzo Salamone;Giacomo Cuttone;Giuseppe Antonio Pablo Cirrone;Andrea Russo;Teresio Avitabile;Corrado Spatola
2018-01-01

Abstract

Introduction: Porocarcinoma is a rare sort of skin cancer developing from eccrine sweat glands, with a very rare location to the eyelid. Surgery is the unique form of treatment reported in the literature. We use radiotherapy for a case of an almost centenary man who suffered from an histologically proven porocarcinoma at the level of the left inferior eyelid. Materials and methods: We made a treatment plan comparison between photon-beam and proton-beam radiotherapy and chose the latter due to the favourable dose distribution of charged particles. Irradiation was delivered through an extreme hypofractionation Results: A rapid complete response was obtained. No relevant effects have been reported and visual function is maintained. Conclusions: This is the first case of use of proton-beam radiotherapy for the treatment of eyelid porocarcinoma. We believe that protontherapy can become a valid alternative to surgery for this type of cancer.
Eccrine; Eyelid porocarcinoma; Proton therapy; Radiotherapy; Medicine (all)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11769/329039
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