Objective: The aim of this study was to investigate and compare the clinical, microbial, and inflammatory effects of a diode laser as an adjunct to scaling and rtxrt planing (SRP) versus SRP alone for the treatment of generalized aggressive periodontitis (GAgP). Methods: Using a split-mouth design, 31 patients with GAgP were enrolled in the study. The maxillary right and left quadrants were randomly assigned to SRP+diode laser or SRP alone. Patients were examined on a regular basis for clinical, microbiological, and inflammatory mediator changes over a 1-year period. Clinical attachment level (CAL) was the primary outcome variable chosen. In addition, subgingival biofilm samples and gingival crevicular fluid (GCF) inflammatory mediators were analyzed at each follow-up session. Results: Compared to baseline, both treatments demonstrated an improvement in periodontal parameters at 1 year. However, SRP+diode laser produced a significant improvement in probing depth (PD; 2.56 ±0.44 vs. 3.36±0.51 mm, p<0.05) and CAL (3.47 ±0.25 vs. 4.11 ±0.26mm, p<0.05) values compared to SRP alone. Similarly, in the SRP+diode laser group, the bacteria of orange complex group were significantly reduced at 30 and 60 days compared to SRP alone. Moreover, SRP+diode laser determined a reduction in mean GCF level of interleukin (IL)-1 p and IL-l/tfIL-10 ratio at 15 and 30 days compared to SRP alone (p<0.05). Conclusions: At I year, SRP+diode laser yielded a significant reduction in some clinical parameters, while microbial and inflammatory mediator changes were not significantly reduced compared to SRP alone.

The effects of diode laser therapy as an adjunct to scaling and root planing in the treatment of aggressive periodontitis: A 1-Year Randomized Controlled Clinical Trial

Isola G.
Writing – Review & Editing
2017

Abstract

Objective: The aim of this study was to investigate and compare the clinical, microbial, and inflammatory effects of a diode laser as an adjunct to scaling and rtxrt planing (SRP) versus SRP alone for the treatment of generalized aggressive periodontitis (GAgP). Methods: Using a split-mouth design, 31 patients with GAgP were enrolled in the study. The maxillary right and left quadrants were randomly assigned to SRP+diode laser or SRP alone. Patients were examined on a regular basis for clinical, microbiological, and inflammatory mediator changes over a 1-year period. Clinical attachment level (CAL) was the primary outcome variable chosen. In addition, subgingival biofilm samples and gingival crevicular fluid (GCF) inflammatory mediators were analyzed at each follow-up session. Results: Compared to baseline, both treatments demonstrated an improvement in periodontal parameters at 1 year. However, SRP+diode laser produced a significant improvement in probing depth (PD; 2.56 ±0.44 vs. 3.36±0.51 mm, p<0.05) and CAL (3.47 ±0.25 vs. 4.11 ±0.26mm, p<0.05) values compared to SRP alone. Similarly, in the SRP+diode laser group, the bacteria of orange complex group were significantly reduced at 30 and 60 days compared to SRP alone. Moreover, SRP+diode laser determined a reduction in mean GCF level of interleukin (IL)-1 p and IL-l/tfIL-10 ratio at 15 and 30 days compared to SRP alone (p<0.05). Conclusions: At I year, SRP+diode laser yielded a significant reduction in some clinical parameters, while microbial and inflammatory mediator changes were not significantly reduced compared to SRP alone.
Aggressive periodontitis; Crevicular fluid; Diode laser; Microbiology; Randomized controlled trials; Scaling and root planing; Adult; Aggressive Periodontitis; Female; Humans; Lasers, Semiconductor; Male; Dental Scaling; Low-Level Light Therapy; Root Planing; Biomedical Engineering; Radiology, Nuclear Medicine and Imaging
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/20.500.11769/346953
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