It is shown that structural changes of the phototoxic anti-cancer drug flutamide after its compartmentalization in unilamellar phospholipid bilayer vesicles lead to a highly selective modification of the photochemical outcome, locking the main photodegradation pathways observed in homogeneous media and unlocking a new and more efficient photoreactive channel. RI Sortino, Salvatore/E-4684-2011

New insight on the photoreactivity of the phototoxic anti-cancer flutamide: photochemical pathways selectively locked and unlocked by structural changes upon drug compartmentalization in phospholipid bilayer vesicles

SORTINO, Salvatore;
2001

Abstract

It is shown that structural changes of the phototoxic anti-cancer drug flutamide after its compartmentalization in unilamellar phospholipid bilayer vesicles lead to a highly selective modification of the photochemical outcome, locking the main photodegradation pathways observed in homogeneous media and unlocking a new and more efficient photoreactive channel. RI Sortino, Salvatore/E-4684-2011
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11769/36061
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 34
  • ???jsp.display-item.citation.isi??? 35
social impact