Amyloid goiter is due to the deposition of amyloid in the thyroid, resulting with enlargement of the gland and compressive symptoms. Case: We herein present a case of a 45-year-old male patient who complained of a big swelling in the neck. Ultrasound showed an enlarged thyroid gland with mediastinal involvement. The multinodular appearance was consistent with the diagnosis of multinodular goiter. He had a history of multiple myeloma but no sign of systemic amyloidosis. Discussion: Thyroid gland was removed and the histopathological examination revealed a diffuse deposition of amyloid associated with metaplastic lipomatosis of the stroma. Conclusions: The treatment of choice in patients with amyloid goiter is total thyroidectomy to solve compression symptoms.

A rare case of primary thyroid amyloidosis

Cannizzaro, M. A.
;
Lo Bianco, S.;SALIBA, WAIEL;D'ERRICO, SARA;PENNETTI PENNELLA, FRANCESCA;Provenzano, D.;Magro, G.
2018

Abstract

Amyloid goiter is due to the deposition of amyloid in the thyroid, resulting with enlargement of the gland and compressive symptoms. Case: We herein present a case of a 45-year-old male patient who complained of a big swelling in the neck. Ultrasound showed an enlarged thyroid gland with mediastinal involvement. The multinodular appearance was consistent with the diagnosis of multinodular goiter. He had a history of multiple myeloma but no sign of systemic amyloidosis. Discussion: Thyroid gland was removed and the histopathological examination revealed a diffuse deposition of amyloid associated with metaplastic lipomatosis of the stroma. Conclusions: The treatment of choice in patients with amyloid goiter is total thyroidectomy to solve compression symptoms.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/20.500.11769/360689
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