The progressive supranuclear palsy is a progressive neurodegenerative disease characterized by Parkinsonism, oculomotor abnormalities, early postural instability and cognitive impairment. Neurodegeneration in PSP is associated with tau protein, but the mechanisms by which tau abnormalities lead to cell dysfunction and death are not well understood. Neuro-behavioural problems related to the fear and loss of autonomy can determinate many bioethical implications. Careful planning involving patients’ families, academic and industry researchers were necessary to ensure improvement in quality of life.
Progressive supranuclear palsy: Neuropsychopathological, therapeutical and bioethical aspects
Vecchio, Ignazio
Membro del Collaboration Group
;Tornali, Cristina
Membro del Collaboration Group
;Malaguarnera, Giulia
;Malaguarnera, Michele
2018-01-01
Abstract
The progressive supranuclear palsy is a progressive neurodegenerative disease characterized by Parkinsonism, oculomotor abnormalities, early postural instability and cognitive impairment. Neurodegeneration in PSP is associated with tau protein, but the mechanisms by which tau abnormalities lead to cell dysfunction and death are not well understood. Neuro-behavioural problems related to the fear and loss of autonomy can determinate many bioethical implications. Careful planning involving patients’ families, academic and industry researchers were necessary to ensure improvement in quality of life.File in questo prodotto:
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