A total of 10 desmoplastic small round-cell tumour patients were treated by high-dose chemotherapy with stem cell support. After high-dose chemotherapy, no complete response conversion was obtained and EWS-WTI fusion transcript detection was positive in the peripheral blood during follow-up in all patients. High-dose chemotherapy did not seem to change the results in desmoplastic small round-cell tumour. © 2003 Cancer Research UK.

Prospective study of high-dose chemotherapy and autologous peripheral stem cell transplantation in adult patients with advanced desmoplastic small round-cell tumour

Soto Parra H.;
2003-01-01

Abstract

A total of 10 desmoplastic small round-cell tumour patients were treated by high-dose chemotherapy with stem cell support. After high-dose chemotherapy, no complete response conversion was obtained and EWS-WTI fusion transcript detection was positive in the peripheral blood during follow-up in all patients. High-dose chemotherapy did not seem to change the results in desmoplastic small round-cell tumour. © 2003 Cancer Research UK.
Desmoplastic small round-cell tumour; High-dose chemotherapy; Abdominal Neoplasms; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; DNA Primers; Humans; Male; Middle Aged; Oncogene Proteins, Fusion; Prognosis; Prospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Survival Rate; Transplantation, Autologous; Treatment Outcome; Peripheral Blood Stem Cell Transplantation
File in questo prodotto:
File Dimensione Formato  
6601304.pdf

accesso aperto

Tipologia: Versione Editoriale (PDF)
Dimensione 158.96 kB
Formato Adobe PDF
158.96 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11769/369788
Citazioni
  • ???jsp.display-item.citation.pmc??? 12
  • Scopus 25
  • ???jsp.display-item.citation.isi??? 24
social impact