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EnglishTwenty-six patients with relapsed or refractory Hodgkin's disease (HD) were treated with an intensive salvage regimen combining ifosfamide (3000 mg/m2/d, days 1-4 through continuous intravenous infusion) and vinorelbine (25 mg/m2, i.v. days 1 and 5) with mesna uroprotection and G-CSF support. Courses were given at 3-week intervals. Ten patients achieved a complete and 10 patients a partial response, yielding an overall response rate of 77%. The main toxic effect was neutropenia and the combination was well tolerated.
| Titolo: | Ifosfamide and vinorelbine: An active regimen for patients with relapsed or refractory Hodgkin's disease |
| Autori interni: | |
| Data di pubblicazione: | 1998 |
| Rivista: | |
| Handle: | http://hdl.handle.net/20.500.11769/369942 |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
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http://hdl.handle.net/20.500.11769/369942
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